Su2017 Increased Leptin Levels in Children With Down's Syndrome

Alterations of several cardiometabolic risk factors, in particular, leptin concentrations and leptin resistance are present in children with DS. The presence of hyperleptinemia without hyperinsulinemia suggests a probable inherent genetic basis for increased leptin resistance in patients with DS. There is a need for larger studies to further understand increased leptin resistance in DS that may contribute to increased CVD related morbidity and mortality in these patients.

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Concentrations of leptin, adiponectin and other metabolic parameters in non-obese children with Down syndrome

Tenneti

Dayal

Sharda

et al. 2017

Journal of Pediatric Endocrinology and Metabolism

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Su2017 Increased Leptin Levels in Children With Down's Syndrome

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Concentrations of leptin, adiponectin and other metabolic parameters in non-obese children with Down syndrome

Concentrations of leptin, adiponectin and other metabolic parameters in non-obese children with Down syndrome

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