Subacute Thyroiditis in a Child

Bilbao, Nordie A.; Kaulfers, Anne-Marie D.; Bhowmick, Samar K.

doi:10.4158/accr-2018-0211

Cited by 8 publications

(6 citation statements)

References 13 publications

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“…Consider thyroid hormone testing and/or other SAT screening methods especially in ICU patients 2. Possible occurrence in young children [ 31 , 32 ] 2. Physicians should be aware about possible SAT occurrence in children; possible atypical course with trachea compression [ 31 ] Clinical course 1.…”

Section: Discussionmentioning

confidence: 99%

“…However, the symptoms of SAT were present in as many as 10–20% of patients hospitalized due to COVID-19 on intensive care units (ICU) and non-intensive care units, respectively [ 18 , 30 ]. Moreover, recently young children affected by SAT have been reported [ 31 , 32 ]. Thus, the clinicians should be aware of a possible presence of SAT in children, including the youngest ones.…”

Section: Epidemiologymentioning

confidence: 99%

“…As it was previously mentioned, some cases of children with SAT have been reported [ 31 , 32 ]. The most spectacular case, published very recently, regarded 5-year-old boy with airway compromise caused by SAT [ 31 ].…”

Section: Current Clinical Manifestation and Factors Modifying Clinical Coursementioning

confidence: 99%

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New aspects in the pathogenesis and management of subacute thyroiditis

Stasiak

Lewiński

2021

Rev Endocr Metab Disord

104

106

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Subacute thyroiditis (SAT) is a thyroid inflammatory disease, whose pathogenesis and determinants of the clinical course were unclear for many decades. The last few years have brought many clinically significant new data on the epidemiology, pathogenesis and management of SAT. Several human leukocyte antigen (HLA) alleles were demonstrated not only to increase the risk of SAT, but also to correlate with SAT clinical course and determine the risk of recurrence. The world-wide epidemic of the coronavirus disease 19 (COVID-19) has provided new observations that the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) can be a potent SAT-triggering factor, and that the clinical course of SAT in patients affected by COVID-19 is different from a typical one. Additionally, many new trends in the clinical course are emerging. In the last years, painless course of SAT is more and more often described, constituting a special challenge in patients hospitalized due to COVID-19. Despite an excellent availability of diagnostic methods, several difficulties in SAT differential diagnosis can be currently encountered and the proper diagnosis and treatment is frequently delayed. False positive diagnoses of SAT in patients with malignancies of poor prognosis constitute a life-threatening problem. Taking into account all the new aspects of SAT pathogenesis and of its clinical course, the new – modified – SAT diagnosis criteria have been proposed.

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Section: Discussionmentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

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New aspects in the pathogenesis and management of subacute thyroiditis

Stasiak

Lewiński

2021

Rev Endocr Metab Disord

104

106

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“…However, the symptoms suggestive of SAT are present in 10% and 20% of ICU-admitted patients with COVID-19 and those hospitalized in non-ICU wards due to this disease, respectively [22,23]. Moreover, some pediatric cases of SAT have been reported recently [32,33]. Stasiak et al showed that the susceptibility to SAT and the chance of recurrent SAT could be related to HLA [34,35].…”

Section: Discussionmentioning

confidence: 99%

SARS-CoV-2 and Subacute Thyroiditis: A Case Report and Literature Review

Salehi

Mohammadi

et al. 2022

Case Reports in Medicine

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Introduction. Subacute thyroiditis (SAT) is an inflammatory disorder of the thyroid gland, usually triggered by a recent viral or bacterial infection of upper respiratory tracts. The disease is characterized by neck pain radiating to the ears and thyroid gland tenderness. In most cases, it is associated with a transient episode of hyperthyroidism, which is followed by euthyroidism. However, sometimes, it manifests itself with hypothyroidism. Case Presentation. The present report described a case of SAT who was a 55-year-old man presenting to an endocrine clinic with tachycardia, tremor, and neck pain radiating to the jaw and ears. His thyroid function test revealed thyrotoxicosis, and thyroid ultrasound findings were consistent with SAT. The patient reported a history of COVID-19 about 15 days before presentation, which was confirmed by a positive PCR test for SARS-CoV-2. Conclusions. It is of great importance for physicians to note that thyrotoxicosis in a patient with a recent history of COVID-19 can be due to SAT. Therefore, they should not begin antithyroid drugs without ordering proper investigations.

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“…Patients with AST and SAT present with similar symptoms (fever, anterior cervical pain, thyroid swelling/tenderness) as well as similar imaging findings, thereby posing difficulties in distinguishing between the two conditions ( 4 , 5 ). However, the two diseases differ considerably in severity.…”

Section: Discussionmentioning

confidence: 99%

Subacute thyroiditis presenting with creeping in a 6-year-old boy

Nakamura

Kakimoto

Morita

et al. 2021

Clin Pediatr Endocrinol

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Among the types of acute thyroiditis, subacute thyroiditis (SAT) is rare in children, and there is limited knowledge regarding its characteristics in pediatric cases. We present a case of SAT in a 6-yr-old boy who was brought to our hospital with high fever and pain in the front portion of the neck. Acute suppurative thyroiditis (AST), which is common in children, was suspected initially. Tenderness observed in the thyroid corresponded to a hypoechoic region on ultrasonography. The tenderness subsequently shifted to the isthmus, which was evident as a hypoechoic region on ultrasonography. Movement of hypoechoicity is typical of creeping thyroiditis, wherein the pain and tenderness can be unilateral or may start on one side and subsequently shift to the contralateral side after days or even weeks. Based on this characteristic and changes in laboratory parameters, the patient was diagnosed as a case of creeping thyroiditis. Improvement was observed in the patient without the use of anti-inflammatory drugs. At the 2-yr follow-up, the patient did not have thyrotoxicosis or relapse. Although AST is more prevalent than SAT in children, ultrasonography findings of creeping thyroiditis may be an important indicator for the diagnosis of SAT in pediatric patients.

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Subacute Thyroiditis in a Child

Cited by 8 publications

References 13 publications

New aspects in the pathogenesis and management of subacute thyroiditis

New aspects in the pathogenesis and management of subacute thyroiditis

SARS-CoV-2 and Subacute Thyroiditis: A Case Report and Literature Review

Subacute thyroiditis presenting with creeping in a 6-year-old boy

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