Subclinical ventricular repolarization abnormality in uncontrolled compared with controlled treated hypertension

Al-Nimer, Marwan S.M.; Hussein, Ismail I.

doi:10.1016/j.ihj.2016.07.021

Cited by 2 publications

(5 citation statements)

References 34 publications

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“…Stiffening of arteries leads to increased cBP, which indicates increased LVH and associated comorbidities such as arrhythmias. 7,11,37,40 Despite increased PWV and cBP levels in patients with CSK, we did not observe any increase in LVMI or tendency for ventricular arrhythmia or sudden cardiac death. To the best of our knowledge, this is the first study assessing the ventricular repolarization parameters in patients with CSK.…”

Section: Discussioncontrasting

confidence: 65%

“…This finding should be checked in larger series. On the other hand, we may consider that PWV determined along with ABPM by the same device may be beneficial in children with CSK.Stiffening of arteries leads to increased cBP, which indicates increased LVH and associated comorbidities such as arrhythmias 7,11,37,40. Despite increased PWV and cBP levels in patients with CSK, we did not observe any increase in LVMI or tendency for ventricular arrhythmia or sudden cardiac death.…”

mentioning

confidence: 63%

“…Over the last few years, cBP has been recommended to be assessed in children with HT, even in the early childhood period 8,9 . Besides, arrhythmia risk determined by elongation in ventricular repolarization indices has been increased in patients with hypertension 11,12,13 …”

Section: Introductionmentioning

confidence: 99%

“…8,9 Besides, arrhythmia risk determined by elongation in ventricular repolarization indices has been increased in patients with hypertension. 11,12,13 We have hypothesized that patients with CSK might be at risk for all of the abovementioned cardiovascular risks since they are more prone to HT. To the best of our knowledge, no study on vascular stiffness, cBP, or ventricular repolarization parameters has been conducted in children with a unilateral functioning kidney.…”

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confidence: 99%

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Cardiovascular risk assessment in children and adolescents with congenital solitary kidneys

Kasap-Demir¹,

Soyaltın²,

Alparslan³

et al. 2021

J of Clinical Hypertension

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It is well known that patients with solitary kidneys (SKs) are at risk of hypertension (HT), proteinuria, and glomerulosclerosis due to their low number of nephrons. 1-4 They tend to have higher levels of HT-associated end-organ damage markers, such as left ventricular mass index (LVMI) and microalbuminuria. 5 Congenital SKs (CSKs) or acquired SKs (ASKs) have different effects on glomerular filtration rate (GFR) and blood pressure (BP).

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Section: Discussioncontrasting

confidence: 65%

mentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Cardiovascular risk assessment in children and adolescents with congenital solitary kidneys

Kasap-Demir¹,

Soyaltın²,

Alparslan³

et al. 2021

J of Clinical Hypertension

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“… 10 , 11 Moreover, indices of ventricular repolarisation, including JTc interval and Tp-e/QTcB index, were significantly worse in NAFLD patients, which indicates that these patients have a significantly higher risk of ventricular arrhythmias. 17 , 18 …”

Section: Discussionmentioning

confidence: 99%

A preliminary report about the detection of ventricular repolarisation in patients with non-alcoholic fatty liver disease

Al-Nimer

Esmail

et al. 2020

Journal of Taibah University Medical Sciences

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Objectives Non-alcoholic fatty liver disease (NAFLD) is a multisystem disease which can affect the cardiovascular system as well. We conducted this study to determine the cardiac effects of NAFLD such as conduction of impulse and ventricular repolarisation on electrocardiography (ECG). Methods In this study, we recruited patients with risk factors for NAFLD (group I; n = 23) and NAFLD patients (group II; n = 74) from Shar Hospital in Sulaimani City, Iraq. We analysed anthropometric measurements, serum fasting lipid profile, glucose levels, liver enzymes, and ECG recordings. Results ECG recordings showed significantly longer PR intervals, significantly shorter QTcB and JTc intervals, and a higher Tp-e/QTcB ratio in group II patients than in group I patients. These abnormalities were not associated with risk factors for diabetes. The TQ duration was significantly correlated with serum alanine aminotransferase (r = 0.411, p < 0.001) and aspartate aminotransferase (r = 0.272, p = 0.019) levels. Conclusion In our study, the presence of significant abnormalities in ventricular repolarisation suggests that patients with newly diagnosed NAFLD have subclinical cardiac stress and a higher risk of ventricular arrhythmias.

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Subclinical ventricular repolarization abnormality in uncontrolled compared with controlled treated hypertension

Abstract: Patients with hypertension have variability in ventricular repolarization (QTcB and JT) irrespective of their blood pressure control putting them at higher risk of cardiac arrhythmias.

Cited by 2 publications

References 34 publications

Cardiovascular risk assessment in children and adolescents with congenital solitary kidneys

Cardiovascular risk assessment in children and adolescents with congenital solitary kidneys

A preliminary report about the detection of ventricular repolarisation in patients with non-alcoholic fatty liver disease

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