Subhypnotic doses of midazolam prevents nausea and vomiting due to spinal anaesthesia for cesarean section

Effects of intravenous midazolam during spinal anaesthesia for caesarian section

“…The incidence of nausea in control group is similar to incidence reported by D. Ure et al 4 The lower rate of nausea in midazolam group is similar to finding of O. Tarhan et al 5 The mechanism of anti-emetic effect of midazolam is not well known. Midazolam acts on chemoreceptor trigger zone to reduce synthesis, release and postsynaptic effect of dopamine.…”

The Effects of Acupuncture on Nausea and Vomiting and Consumption of Propofol in Cesarean Section Performed With Spinal Anesthesia

“…Intra-operative nausea and vomiting rate was observed as 46.15% in the same study. The most commonly used method for the treatment of nausea and vomiting observed due to hypotension formed by the effects of spinal anesthesia is the use of vasopressor medications, especially the use of ephedrine in order to prevent hypotension (7,19). Considering the side effects of ephedrine used for the treatment of hypotension that occurs after spinal anesthesia in caesarean operations performed under spinal anesthesia, studies have been conducted to identify different doses of ephedrine or new drugs and techniques that can be used instead of ephedrine (4,5,16,21).…”

“…The most frequent comorbid clinical case of hypotension is nausea and vomiting (6). In addition, the probability of vomiting and nausea is very high in the later phases of operations in the period in which the peritoneum is holding after the birth of newborn and clinical conditions causing by this can lead very serious side effects, including aspiration pneumonia (7)(8)(9). In addition, the amount of money spent for nausea and vomiting has been shown to be greater than those expended for postoperative analgesia (10).…”

“…Several studies in the literature generally focused on drug applications in order to prevent nausea and vomiting which are expected to be occurred in cesarean sections performed under spinal anesthesia (1,2,7,11). The most preferred method for the prevention of nausea and vomiting occurring during cesarean section is administration of subhypnotic doses (1 mg/kg) of propofol (7,11).…”

“…The most preferred method for the prevention of nausea and vomiting occurring during cesarean section is administration of subhypnotic doses (1 mg/kg) of propofol (7,11). However, the side effects that may occur due to the applications of these drugs should also be paid attention.…”