Subjective memory complaints, education, and risk of Alzheimer's disease

Oijen, Marieke van; Jong, Frank Jan de; Hofman, Albert; Koudstaal, Peter J.; Breteler, Monique M.B.

doi:10.1016/j.jalz.2007.01.011

Cited by 208 publications

(181 citation statements)

References 13 publications

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“…Apesar de os resultados atuais não sugerirem relação entre escolaridade e queixas cognitivas, é possível que ela exista de forma modesta, sendo detectável apenas por meio de estudos longitudinais, com amostras maiores. Em análise realizada no estudo de Rotterdam 14 , por exemplo, concluiu-se que o risco para desenvolvimento da doença de Alzheimer era maior em pessoas com queixas subjetivas de memória quando elas apresentavam escolaridade elevada, e, entre estas, nas que obtêm bom desempenho em testes cognitivos formais, a queixa de memória pode ser o primeiro sinal da doença de Alzheimer. A queixa de memória era menos preditiva de doença de Alzheimer entre pessoas de baixa escolaridade.…”

Section: Discussionunclassified

“…Os autores destacam, ainda, a possibilidade de as queixas serem fator preditivo para a demência em indivíduos com alta escolaridade, mesmo quando não são identificados prejuízos cognitivos em avaliações breves. Estudo longitudinal recente 14 destacou a importância da queixa de memória entre idosos altamente escolarizados para a detecção precoce do declínio cognitivo.…”

Section: Introductionunclassified

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Queixas de memória de idosos e sua relação com escolaridade, desempenho cognitivo e sintomas de depressão e ansiedade

Paulo

Yassuda

2010

Rev. psiquiatr. clín.

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Queixas de memória de idosos e sua relação com escolaridade, desempenho cognitivo e sintomas de depressão e ansiedadeThe relation between memory complaints in the elderly and education, cognitive performance, and symptoms of depression and anxiety Paulo DLV, Yassuda MS / Rev Psiq Clín. 2010;37(1):23-6Palavras-chave: Queixas de memória, envelhecimento, escolaridade, idosos, depressão, ansiedade. AbstractBackground: Older adults with mnemonic deficits may complain about memory more frequently. Memory complaints may be more frequent among older adults with lower education, due to greater vulnerability to cognitive decline. Objectives: To investigate if memory complaints vary as a function of education, and to evaluate if memory complaints are associated with cognitive performance, and symptoms of depression and anxiety. Methods: Sixty seven older adults (between 60-75 years) were divided into three groups: 1-4 years of education (n = 23), 4-8 years (n = 20), and 9 or more (n = 24). The protocol included the Mini-Mental State Examination (MMSE), Brief Cognitive Battery (BCB) − memorization of 10 pictures, Verbal Fluency Animal Category (VF), Clock Drawing Test (CDT) −, a questionnaire about frequency of forgetting, the Memory Complaint Questionnaire (MAC-Q), the Geriatric Depression Scale (GDS), and the Beck Anxiety Inventory (BAI). Results: Significant differences were observed among the three groups for the MMSE, 10-picture recognition, VF, and CDT, and no significant differences were found for frequency of forgetting and MAC-Q. Also, there was no association between complaints and cognitive performance, or complaints and depressive symptoms, however, the correlation between frequency of forgetting and symptoms of anxiety was significant. Discussion: Memory complaints were not associated to education, cognitive performance, or depressive symptoms, yet, they were associated with anxiety symptoms.

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Section: Discussionunclassified

Section: Introductionunclassified

Queixas de memória de idosos e sua relação com escolaridade, desempenho cognitivo e sintomas de depressão e ansiedade

Paulo

Yassuda

2010

Rev. psiquiatr. clín.

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“…Earlier research has shown that among people with higher education these complaints might be an important indicator of impending Alzheimer's disease (AD) [17][18][19][20][21] . In a nine-year longitudinal study, Van Oijen et al 17 demonstrated that among seniors with higher educational levels, even when they achieved normal results on cognitive tests, complaints were predictive of AD. Clinical studies have also suggested that complaints could be of better predictive value for dementia among highly educated individuals, even when no cognitive impairment is observed in brief tests 18,19 .…”

Section: Introductionmentioning

confidence: 99%

Relations between memory complaints, depressive symptoms and cognitive performance among community dwelling elderly

Silva¹,

Lima-Silva²,

Falcão³

et al. 2014

Rev. psiquiatr. clín.

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Relations between memory complaints, depressive symptoms and cognitive performance among community dwelling elderly AbstractBackground: Memory complaints are quite common among the elderly; yet, the clinical relevance of these complaints to diagnose cognitive decline is debatable, since several different factors could be associated with them. Objective: The present paper examined the correlations between memory complaints, depressive symptoms and cognitive performance in a group of 301 elderly individuals who lived in the district of Ermelino Matarazzo, São Paulo, and who participated in the population-based survey entitled Profiles of Frailty in Elderly Brazilians by the FIBRA Network. Methods: Cognitive performance was assessed with the memorization test involving 10 common pictures, the Mini Mental State Examination (MMSE), the Verbal Fluency (VF) test, and the Clock Drawing Test, which comprise the Brief Cognitive Screening Battery (BCSB). Memory complaints were assessed with the Memory Complaint Questionnaire (MAC-Q), and depressive symptoms with the Geriatric Depression Scale (GDS). Results: Female participants had higher rates of memory complaints when compared to male participants (p = 0.013). Subjects with less years of schooling had more severe memory complaints and poorer cognitive performance than those with more years of schooling (p < 0.003). The presence of depressive symptoms was associated with poorer memory assessment scores (r = 0.39, p < 0.001). Discussion: Memory complaints were correlated with sex, schooling and depressive symptoms among elderly individuals residing in the community. No correlation was found between complaints and cognitive performance.Silva LSV, et al. / Rev Psiq Clín. 2014;41(3):67-71 Keywords: Older adults, elderly, memory, depressive symptoms, memory complaints. ResumoContexto: A queixa de memória é comum entre pessoas idosas, entretanto sua relevância clínica para o diagnóstico de alterações cognitivas é questionável, visto que diversos fatores podem se associar às queixas. Objetivo: O presente estudo avaliou a relação entre queixas de memória, sintomas depressivos e desempenho cognitivo em 301 idosos residentes em Ermelino Matarazzo que participaram da pesquisa de base populacional Perfis de Fragilidade em Idosos Brasileiros da Rede FIBRA. Métodos: O desempenho cognitivo foi avaliado por meio dos testes de memorização de 10 figuras comuns, Miniexame do Estado Mental (MEEM), Fluência Verbal (FV) e Teste do Desenho do Relógio, que compõem a Bateria Breve de Rastreio Cognitivo (BBRC). As queixas de memória foram avaliadas pelo Questionário de Queixas de Memória (MAC-Q) e os sintomas depressivos, pela Escala de Depressão Geriátrica (EDG). Resultados: Participantes do sexo feminino apresentaram maior índice de queixas de memória, comparado aos homens (p = 0,013). Idosos menos escolarizados apresentaram queixas de memória mais intensas e pior desempenho cognitivo, comparados aos de maior escolaridade (p < 0,003). A presença de sintomas depressivos associou-se a pior ava...

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“…Subjective cognitive decline (SCD) is actually considered to be associated with an increased likelihood of future cognitive impairment and dementia, especially among those who worry about their memory [1][2][3]. According to the suggestions made by the Working Group of the Subjective Cognitive Decline Initiative (SCD-I) [4], SCD is defined as personal complaints about one´s cognitive state in the absence of objective cognitive impairment.…”

Section: Introductionmentioning

confidence: 99%

Worries about Alzheimer’s Disease and Subjective Cognitive Decline in Proxies of AD Patients and Controls

Philipps¹,

Müller²,

Preische³

et al. 2017

J Alzheimers Dis Parkinsonism

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Subjective memory complaints, education, and risk of Alzheimer's disease

Abstract: Especially in persons with a high level of education who still perform well on formal cognitive tests, subjective memory complaints might be an important first sign of imminent Alzheimer's disease.

Cited by 208 publications

References 13 publications

Queixas de memória de idosos e sua relação com escolaridade, desempenho cognitivo e sintomas de depressão e ansiedade

Queixas de memória de idosos e sua relação com escolaridade, desempenho cognitivo e sintomas de depressão e ansiedade

Relations between memory complaints, depressive symptoms and cognitive performance among community dwelling elderly

Worries about Alzheimer’s Disease and Subjective Cognitive Decline in Proxies of AD Patients and Controls

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