Subsidence of a partially porous titanium lumbar cage produced by electron beam melting technology

Distefano, Fabio; Guglielmino, Eugenio; Amata, Aurora; Mineo, Rosalia

doi:10.1002/jbm.b.35176

Cited by 9 publications

(3 citation statements)

References 43 publications

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“…Despite recent advances in biomaterials and tissue engineering, the repair of such a critical bone defects remains a challenge [ 69 , 70 , 71 ]. Lattice materials are widely used in the biomedical field when devices are applied as bone substitutes [ 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 ]. A successful porous metallic implant should restore the physiological function of the bone, and porous structures provide high interfacial bond area for vascularization and bone ingrowth, promoting the biological fixation of implants and bone [ 80 ].…”

Section: Mechanical and Morphological Requirements For Biomedical App...mentioning

confidence: 99%

Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review

Distefano

Pasta

2023

JFB

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The progress in additive manufacturing has remarkably increased the application of lattice materials in the biomedical field for the fabrication of scaffolds used as bone substitutes. Ti6Al4V alloy is widely adopted for bone implant application as it combines both biological and mechanical properties. Recent breakthroughs in biomaterials and tissue engineering have allowed the regeneration of massive bone defects, which require external intervention to be bridged. However, the repair of such critical bone defects remains a challenge. The present review collected the most significant findings in the literature of the last ten years on Ti6Al4V porous scaffolds to provide a comprehensive summary of the mechanical and morphological requirements for the osteointegration process. Particular attention was given on the effects of pore size, surface roughness and the elastic modulus on bone scaffold performances. The application of the Gibson–Ashby model allowed for a comparison of the mechanical performance of the lattice materials with that of human bone. This allows for an evaluation of the suitability of different lattice materials for biomedical applications.

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Section: Mechanical and Morphological Requirements For Biomedical App...mentioning

confidence: 99%

Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review

Distefano

Pasta

2023

JFB

Self Cite

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“…87 Three-dimensional printing of soft biomaterials, biomaterial-celldrug combinations and 3D printing of hard biomaterials have all seen increased attention in the past year. These works have investigated the range of 3D printing from electron-beam printing of titaniumbased spinal cages 91 to 3D printing of Hydroxyapatite and/or polymeric hydrogel biomaterials. Three-dimensional printing of gelatinbased hydrogels 92,93 for bone and cartilage applications was reported as were printed PEEK hip stems 94 and hydroxyapatite-based biomaterials.…”

Section: Biomaterials Research In Advanced Materials (Ekaterina Peret...mentioning

confidence: 99%

The Year 2022 in biomaterials research: A perspective from the editors of six leading journals

Stegemann

Wagner

Göbel

et al. 2023

J Biomedical Materials Res

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The field of biomaterials science is highly active, with a steadily increasing number of publications and new journals being founded. This article brings together contributions from the editors of six leading journals in the area of biomaterials science and engineering. Each contributor highlights specific advances, topics, and trends that have emerged through the publications in their respective journal in the calendar year 2022. It presents a global perspective on a wide range of material types, functionalities, and applications. The highlighted topics include a diversity of biomaterials; from proteins, polysaccharides, and lipids to ceramics, metals, advanced composites, and a variety of new forms of these materials. Important advances in dynamically functional materials are presented, including a range of fabrication techniques such as bioassembly, 3D bioprinting and microgel formation. Similarly, several applications are highlighted in drug and gene delivery, biological sensing, cell guidance, immunoengineering, electroconductivity, wound healing, infection resistance, tissue engineering, and treatment of cancer. The goal of this paper is to provide the reader with both a broad view of recent biomaterials research, as well as expert commentary on some of the key advances that will shape the future of biomaterials science and engineering.

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“…Since age, sex, and operation affect titanium cage subsidence, multiple studies have been published on the application of finite element analysis (FEA) and computed tomography (CT) scans to reduce the possible contributing factors for titanium cage subsidence (6). The FEA is a systematic method in medicine and medical engineering to determine the biomechanics of the body and to examine the distribution of mechanical stress before implant placement (7).…”

Section: Introductionmentioning

confidence: 99%

Static Analysis and Design of Innovative Porous Lumbar Interbody Cages

2023

ircmj

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Background: Interbody discs play a major role in maintaining the spine and skeleton structures which may undergo damage. If damage is so severe that the disc cannot be repaired, implants, known as “interbody cages”, should be used. Objectives: The present study aimed to propose a novel design with proper strength and resistance against axial disc torques. Methods: The design and analysis of innovative anatomical cages comprised two stages, namely, cage design according to three different models and finite element analysis (FEA). The designs were based on the spine of a 15-year-old teenager without lumbar disc disease. To model the vertebrae, computed tomography )CT( scans and Digital Imaging and Communications in Medicine (DICOM) files were entered into Mimics Version 10.01 (Materialise Inc., Leuven, Belgium); then, the L4 and L5 spinal segments were modeled. Results: The implants were fixed to the bottom level and subjected to a net force of 1000 N. Additionally, a moment load of 7.5 Nm in flexion, extension, axial rotation, and lateral bending was applied in these three cage models. Considering the application of 1000-N force, maximum and minimum stress and strain distribution rates were presented in three honeycomb, Islamic architecture, and porous gyroid cages. Conclusion: Novel designs for lumbar cages were considered to achieve damping capacity, light weight, and high resistance. Considering the characteristics of the honeycomb, Islamic architecture, and gyroid structures, optimal designs were proposed for lumbar cages to achieve adequate strength and resistance against axial disc torques under normal conditions.

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Subsidence of a partially porous titanium lumbar cage produced by electron beam melting technology

Cited by 9 publications

References 43 publications

Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review

Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review

The Year 2022 in biomaterials research: A perspective from the editors of six leading journals

Static Analysis and Design of Innovative Porous Lumbar Interbody Cages

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