2020
DOI: 10.12775/jehs.2020.10.02.040
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Substance P blockade effects on bone marrow hematopoiesis in secondary chronic inflammation

Abstract: Inflammation is defined by the features of bone marrow hematopoiesis. Thus, an objective of the study was to determine the substance P inhibition effects on bone marrow hematopoiesis in secondary chronic carrageenan-induced inflammation in experimental prospective controlled study on 132 white male WAG rats. On the background of blockade of substance P, the course of inflammation was characterized by a less intense neutrophilic reaction and the development of the lymphocyte component at earlier stages of infla… Show more

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