Substance use and perceived symptom improvement among patients with bipolar disorder and substance dependence

Weiss, Roger D.; Kolodziej, Monika E.; Griffin, Margaret L.; Najavits, Lisa M.; Jacobson, Lara M.; Greenfield, Shelly F.

doi:10.1016/s0165-0327(02)00454-8

Cited by 70 publications

(45 citation statements)

References 7 publications

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“…Há inúme-ras hipóteses que procuram explicar a elevada prevalência de dependência de substâncias associada ao transtorno bipolar. Em uma perspectiva baseada em crenças psicológi-cas, os pacientes com transtorno bipolar buscariam o uso de substâncias como uma forma de aliviar sintomas de humor considerados desagradáveis, como o taquipsiquismo e a irritabilidade 20 . Por outro lado, o uso nocivo de substâncias poderia deflagrar o primeiro episódio maníaco 21 .…”

Section: Discussionunclassified

Comorbidades clínicas e psiquiátricas em pacientes com transtorno bipolar do tipo I

Barbosa

Ferreira

Huguet

et al. 2011

J. bras. psiquiatr.

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Section: Discussionunclassified

Comorbidades clínicas e psiquiátricas em pacientes com transtorno bipolar do tipo I

Barbosa

Ferreira

Huguet

et al. 2011

J. bras. psiquiatr.

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“…This association may arise from the notion that alcohol can be "therapeutic" for anxiety. Some studies have suggested that substance dependence can originate from an attempt to treat a mental disorder (Sonne et al, 1994 andWeiss et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

Comorbid disorders in patients with bipolar disorder and concomitant substance dependence

Mitchell

Brown

Rush

2007

Journal of Affective Disorders

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Objective-Substance dependence is common in bipolar disorder and is associated with an increase in Axis I and II comorbidity. Little research has compareed the relative rates of comorbidity among bipolar patients with dependence on different substances. Methods-TheMini International Neuropsychiatric Interview (M.I.N.I.) was used to assess 166 outpatients involved in one of three clinical trials of medicatiosn for bipolar disorder and substance dependence. Patients had concurrent alcohol dependence, cocaine dependence, or both conditions.Results-Generalized anxiety disorder and current depressed mood were significantly more common in bipolar patients with alcohol dependence than bipolar patients with cocaine dependence. Those with cocaine dependence had significantly higher rates of post-traumatic stress disorder and anti-social personality disorder and were more likely to present in a mixed mood state than patients dependent on alcohol. Cocaine dependent patients were more likely than alcohol dependent patients to have bipolar I relative to bipolar II.Limitations-This is a retrospective, cross-sectional data analysis using the M.I.N.I. for diagnosis.Conclusions-Cocaine dependence and alcohol dependence were associated with different clinical features and comorbid disorders in bipolar patients. The results may help confirm the validity of integrative models of mood, behavioral, anxiety, and personality disorders. Further studies on the causal relationship between substance dependence and concurrent and lifetime Axis I disorders for patients with bipolar disorders are indicated.

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“…Recent studies report that the prevalence of DD in patients attending mental health service and substance misuse services ranges between 55% and 85% [36,37], and an association between SUD and mood and anxiety disorders has been supported by epidemiological and clinical studies [38][39][40][41]. In 2014, in the United States, among adults with a past year SUD, 39.1% had a comorbid psychiatric disorder, whereas, among adults without a past year SUD, only 16.2% had a SMI [42].…”

Section: Epidemiology and Clinical Features Of Dd Patientsmentioning

confidence: 99%

Dual Diagnosis Patients First Admitted to a Psychiatric Ward for Acute Psychiatric Patients: 2-Year Period 2003–2004 versus 2013–2014

Gramaglia¹,

Lombardi²,

Rossi³

et al. 2016

Recent Advances in Drug Addiction Research and Clinical Applications

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Dual diagnosis (DD) is the coexistence of severe mental illness (SMI) and substance use disorder (SUD). The increase of DD observed in recent years has important implications for mental health services organization. The aim of this study is to assess the prevalence and features of DD over a decade, comparing the periods 2003-2004 and 2013-2014. We performed a retrospective study retrieving sociodemographic and clinical data from the medical records of patients at their first admission to the Psychiatric Ward of University Hospital "Maggiore della Carità" in Novara, Italy. Patients with SMI and comorbid SUD (SMI-SUD) and patients with SMI without comorbidity (SMI) were compared in the two periods, 2003-2004 versus 2013-2014. SMI-SUD patients in both 2-year periods were more likely to be male, younger, unemployed, living with parents (or alone, for the 2013-2014 period) rather than with a family of their own, and single (or divorced, in 2003-2004). The 2003-2004 patients were more frequently diagnosed with a personality disorder, whereas the 2013-2014 patients had mixed diagnoses. We have found differences in the possible predictors of substance abuse in the two periods as well: in both periods, male gender was associated with an increased risk of DD, whereas age >61 years was associated with decreased risk. Only in the first period (2003)(2004) was having a university degree associated with a decreased risk of DD, whereas the diagnosis of a personality disorder was associated with an increased risk of DD; on the contrary, in the second period (2013)(2014), living in a protective environment was associated with a decreased risk of DD. The identification of changes in the prevalence of first admission DD patients and their clinical and sociodemographic features may help to highlight an evolving pattern of substance use and to identify possible risk factors that may be the target of prevention and treatment approaches.

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Substance use and perceived symptom improvement among patients with bipolar disorder and substance dependence

Cited by 70 publications

References 7 publications

Comorbidades clínicas e psiquiátricas em pacientes com transtorno bipolar do tipo I

Comorbidades clínicas e psiquiátricas em pacientes com transtorno bipolar do tipo I

Comorbid disorders in patients with bipolar disorder and concomitant substance dependence

Dual Diagnosis Patients First Admitted to a Psychiatric Ward for Acute Psychiatric Patients: 2-Year Period 2003–2004 versus 2013–2014

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