Substance Use and Psychosocial Functioning in a Sample of Liver Transplant Recipients with Alcohol-Related Liver Disease

Sacco, Paul; Sultan, Samuel; Tuten, Michelle; Powell, Jessica M.; Connelly, Mark; Barth, Rolf N.; Hodorowicz, Mary; LaMattina, John C.

doi:10.1016/j.transproceed.2018.07.003

Cited by 13 publications

(12 citation statements)

References 20 publications

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“…Some of the studies utilized a survey method; for example, Sacco et al (2018) developed a comprehensive survey to examine substance use and psychosocial and mental health variables in a group of individuals who received a liver transplant and were diagnosed with alcohol-related liver disease. The participants were emailed and then contacted by phone calls, inviting them to participate in the study [24]. Similarly, Lamba (2012) also used a mailed questionnaire [25].…”

Section: Characteristics Of the Included Studiesmentioning

confidence: 99%

“…The other studies employed a cross-sectional assessment of data [10,26]. One study also used incentives for participating in the study [24]. Only one study specified if the participants underwent only one type of transplant vs. multi-organ transplant and or if the transplant was the first transplant vs. repeat transplant [20].…”

Section: Characteristics Of the Included Studiesmentioning

confidence: 99%

“…Thirteen studies reported the rates of illicit substance use in solid-organ transplant candidates ( Table 1). Seven studies reviewed retrospective data [13][14][15][16][17][18]22], three studies used crosssectional assessment [10,[25][26], one study analyzed the national transplant registry [23], one study utilized prospective study design [19], and one study used a survey [24] to collect data. The sample sizes of these studies ranged from 59 [16] to 52,689 [23].…”

Section: Illicit Substance Use Among Solid-organ Transplant Candidatesmentioning

confidence: 99%

“…Eight studies were on liver transplant, three on kidney transplant, and two on cardiac transplantation. Three studies primarily focused on cannabis use [13,23], one on injection drug use (IDU) [16], three studies did not present data on individual substances [18,[24][25], and the others presented data on multiple substances. In the overall cohort, any illicit drug was used by 35% at some point in time, most frequently cannabis (31%), amphetamine (16%), heroin (5%), cocaine, inhalants, and hallucinogens (8% each)…”

Section: Illicit Substance Use Among Solid-organ Transplant Candidatesmentioning

confidence: 99%

“…The majority of the studies included in this review indicate that the most prevalent substance use among patients undergoing liver transplant is cannabis [15,22,24,26]. For example, Schult (2019) included liver transplant recipients with alcoholic liver cirrhosis (ALC), HCV, or Hepatocellular carcinoma (HCC) but without ALC and patients with other liver diseases [26].…”

Section: Liver Transplantmentioning

confidence: 99%

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A Review of the Prevalence of Illicit Substance Use in Solid-Organ Transplant Candidates and the Effects of Illicit Substance Use on Solid-Organ Transplant Treatment Outcomes

Majumder¹,

Sarkar²

2020

Cureus

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Solid-organ transplantation is one of the significant advances in the medical field that have improved the quality of life and survival rates of numerous patients with end-organ dysfunction. Substance use is a common condition of individuals who are in need of solidorgan transplantation. The implications of substance use on solid-organ transplants are gaining increasing attention over the past decade. The current review seeks to explore the prevalence rate of illicit substance use among those who receive solid-organ transplantation (pre and post-transplant) and whether illicit substance use before solid-organ transplantation affects the outcome of solid-organ transplants. We searched the Medline database for all the articles available in English on the prevalence of substance use in the context of solid-organ transplant and the effect on outcome measures. We found 21 relevant articles. It appears that substance use is fairly common among solid-organ transplant candidates, with cannabis being the most common substance of abuse. A heterogeneous sample precludes the drawing of a clear-cut conclusion. But it appears that substance use may affect various outcomes of solidorgan transplants. The existing literature may not be sufficient to adequately assess the risk but limited evidence indicates that illicit substance use, particularly cannabis use, may not affect the overall survival following a solid-organ transplant.

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Section: Characteristics Of the Included Studiesmentioning

confidence: 99%