Substituição valvar isolada com próteses metálicas St. Jude Medical em posição aórtica ou mitral: seguimento de médio prazo

Rodrigues, Alfredo José; Évora, Paulo Roberto Barbosa; Bassetto, Solange; Alves, Lafaiete; Filho, Adilson Scorzoni; Vicente, W.

doi:10.1590/s0066-782x2009000900014

Cited by 3 publications

(3 citation statements)

References 18 publications

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“…In view of the various factors that affect the response to warfarin [ 18 ] , including the intake of vitamin K (more present in some foods, such as avocados, broccoli, spinach and cauliflower [ 16 ] ), adherence to treatment [ 22 ] , genetic factors, drug interactions [ 23 ] , age [ 15 ] , comorbidities, socioeconomic factors [ 24 ] , among others, becomes necessary the publication of more studies to investigate these factors in order to reduce the incidence of complications related to anticoagulation, yet very common in our environment.…”

Section: Discussionmentioning

confidence: 99%

Anticoagulation Quality and Complications of using Vitamin K Antagonists in the Cardiac Surgery Outpatient Clinic

Costa

Krum

Geraldino

et al. 2016

Brazilian Journal of Cardiovascular Surgery

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INTRODUCTION:In patients with mechanical prosthetic heart valves or atrial fibrillation requiring anticoagulation to prevent thromboembolic events, several factors influence adherence and anticoagulation complications.OBJECTIVE:To evaluate the factors that interfere with the quality and complications of anticoagulation with vitamin K antagonists.METHODS:A retrospective cohort study of 100 patients, in the period from 2011 to 2014, was performed. Anticoagulation conditions in the last year, regarding the presence of complications (embolisms/bleeding) and inadequate treatment were assessed: achievement of less than 8 annual prothrombin times and International Normalized Ratio outside therapeutic target in more than 40% of prothrombin times.RESULTS:There were 31 complications (22 minor bleeding without hospitalization and 9 major complications: 7 bleeding with hospitalization and two emboli); 70 were with International Normalized Ratio outside the target in more than 40% of the tests and 36 with insufficient number of prothrombin times. Socioeconomic factors, anticoagulant type and anticoagulation reason had no relationship with complications or with inadequate treatment. There were more complications in patients with longer duration of anticoagulation (P=0.001). Women had more International Normalized Ratio outside the target range (OR 2.61, CI:1.0-6.5; P=0.04). Patients with lower number of annual prothrombin times had longer times of anticoagulation (P=0.03), less annual consultations (P=0.02) and less dose adjustments (P=0.003). Patients with longer duration of anticoagulation have more complications (P=0.001).CONCLUSION:There was a high rate of major complications and International Normalized Ratio was outside the goal. Less annual prothrombin times was related to longer duration of anticoagulation, less annual consultations and less dose adjustments. More major complications occurred in patients with longer duration of anticoagulation.

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Section: Discussionmentioning

confidence: 99%

Anticoagulation Quality and Complications of using Vitamin K Antagonists in the Cardiac Surgery Outpatient Clinic

Costa

Krum

Geraldino

et al. 2016

Brazilian Journal of Cardiovascular Surgery

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“…Dalva et al described initial results of intermittent annular reduction with Alfieri’s repair for the treatment of mitral insufficiency in children 32. A midterm follow up of patients undergoing mitral and aortic valve replacement with the St. Jude Medical valve was the subject of a study by Rodrigues et al,33 while De Bacco et al discussed risk factors for hospital mortality in valve replacement with a mechanical prosthesis 34…”

Section: Methodsmentioning

confidence: 99%

A review of cardiopulmonary research in Brazilian medical journals: clinical, surgical and epidemiological data

Serrano

Silva

2010

Clinics

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Research in the field of cardiopulmonary disease in Brazil has been very active in recent decades. The combination of PUBMED, SCieLO, open access and online searching has provided a significant increase in the visibility of Brazilian journals. This newly acquired international visibility has in turn resulted in the appearance of more original research reports in the Brazilian scientific press. This review is intended to highlight part of this work for the benefit of the readers of “Clinics.” We searched through PUBMED for noteworthy articles published in Brazilian medical journals included in the Journal of Citation Reports of the Institute of Scientific Information to better expose them to our readership. The following journals were examined: “Arquivos Brasileiros de Cardiologia,” “Arquivos Brasileiros de Endocrinologia e Metabologia,” “Brazilian Journal of Medical and Biological Reviews,” “Jornal Brasileiro de Pneumologia,” “Jornal de Pediatria,” “Revista Brasileira de Cirurgia Cardiovascular,” “Revista da Associação Médica Brasileira,” Revista da Escola de Enfermagem U.S.P.” and “São Paulo Medical Journal.” These journals publish original investigations in the field of cardiopulmonary disease. The search produced 71 references, which are briefly examined.

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“…В исследовании A.J. Rodrigues et al [41] сообщается, что летальность, связанная с клапаном, при использовании протеза St. Jude в груп пе протезирования аортального клапана составила 11,3%, из них на долю кровотечений и тромбоэм болий приходилось 78%. В группе протезирования митрального клапана 14% смертей были связаны с клапаном, из них 89% приходились на кровотечение и тромбоэмболии.…”

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Structural evolution of mechanical heart valves (review)

Lepilin,

Bogachev-Prokophiev,

Zhulkov

et al. 2023

RJTAO

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Prosthetic heart valves are widely used biomedical devices. The need for these prostheses is increasing due to the increasing life expectancy of the general population and the consequent incidence of age-related degenerative valvular defects. However, even though mechanical prosthetic valves have been significantly modernized over the last decades, they are still associated with several life-threatening complications, the main one being thrombosis. Addressing this problem is challenging and requires collaboration between bioengineering and cardiothoracic surgery. Thus, the problem of creating the most adapted model of prosthetic heart valve (PHV) turns out to be at the confluence of sciences – medicine, biology, applied mechanics, mathematical modeling, etc. Today, it seems clear that the engineering ideas for hemodynamic adaptation of PHV models have been fully developed. However, research in the field of materials science, as well as a search for surface modification methods, remain a pressing bioengineering challenge.

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Substituição valvar isolada com próteses metálicas St. Jude Medical em posição aórtica ou mitral: seguimento de médio prazo

Abstract: SummaryBackground: In our country, the biological valvular prostheses predominate, considering the difficulties related to anticoagulation, even in young patients, in spite of the need for repeated operations due to the degeneration of the bioprostheses.

Cited by 3 publications

References 18 publications

Anticoagulation Quality and Complications of using Vitamin K Antagonists in the Cardiac Surgery Outpatient Clinic

Anticoagulation Quality and Complications of using Vitamin K Antagonists in the Cardiac Surgery Outpatient Clinic

A review of cardiopulmonary research in Brazilian medical journals: clinical, surgical and epidemiological data

Structural evolution of mechanical heart valves (review)

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