Successful pregnancy following novel IVF protocol and transmyometrial embryo transfer after radical vaginal trachelectomy

Jamal, Wael; Phillips, Simon; Hemmings, Robert; Lapensée, Louise; Couturier, Bernard; Bissonnette, François; Kadoch, Isaac Jacques

doi:10.1016/s1472-6483(10)60017-x

Cited by 16 publications

(8 citation statements)

References 14 publications

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“…Sometimes, however, cannulation of the cervical canal for embryo or blastocyst transfer is not possible. Because tubal transfer usually requires a laparoscopy, transmyometrial transfer under ultrasound guidance is a less invasive option (8). Our failure with the transmyometrial transfers may have been due to increased myometrial contractility impairing implantation (9); as a result, we switched to tubal transfer.…”

Section: Discussionmentioning

confidence: 98%

Successful tubal blastocyst transfer after laparoscopic cervical cerclage: cesarean delivery of a live very low-birth-weight infant and later hysterectomy for uterine rupture

Murray¹,

Hutton²

2011

Fertility and Sterility

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Section: Discussionmentioning

confidence: 98%

Successful tubal blastocyst transfer after laparoscopic cervical cerclage: cesarean delivery of a live very low-birth-weight infant and later hysterectomy for uterine rupture

Murray¹,

Hutton²

2011

Fertility and Sterility

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“…Transmyometrial embryo transfers have been reported in 15 studies: 11 case reports, 3 case series, and one randomized clinical trial ( Khairy et al ., 2016 ; Huberlant et al ., 2014 ; Muñoz et al ., 2014 ; Sullivan-Pyke et al ., 2014 ; Lin et al , 2010 ; Jamal et al ., 2009 ; Ohl et al ., 2009 ; Xu et al ., 2009 ; Lai et al ., 2001 ; Anttila et al ., 1999 ; Lesny et al ., 1999 ; Asaad & Carver-Ward, 1997 ; Groutz et al ., 1997 ; Sharif et al ., 1996 ; Kato et al ., 1993 ). The results reported in these studies are controversial because the inclusion criteria are heterogeneous.…”

Section: Discussionmentioning

confidence: 99%

Transmyometrial embryo transfer as a useful method to overcome difficult embryo transfers - a single-center retrospective study

Ferreri

Portillo

Peñarrubia

et al. 2018

JBRA Assisted Reproduction

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ObjectivePregnancy after an embryo transfer depends largely on embryo quality, endometrial receptivity, and the technique used in the embryo transfer. Embryo transfers have been reported as inevitably traumatic and difficult for 5-7% of patients in assisted reproduction treatment. In these cases, transmyometrial embryo transfer should be considered as a suitable method to overcome difficult embryo transfers. The aim of this study was to report our experience with this technique and analyze its causes, results and complications.MethodsSince 1993, 39 women (40 cycles of assisted reproductive technology treatment) were submitted to transmyometrial embryo transfers in our center. The procedures were carried out as described by the Towako group.ResultsThe enrolled female patients had a mean age of 34 years and a mean baseline FSH level of 6.89 IU/mL. The median number of retrieved oocytes was 7.50 and a mean of 2.63 embryos were transferred. Implantation rate was 9.5%. With respect to clinical results, pregnancy and miscarriage rates were 25% and 30%, respectively. Since there were two twin pregnancies, the live birth rate was 22.5% (9/40). No major complications were reported.ConclusionTransmyometrial embryo transfer can and should be an option in cases of difficult/impossible transcervical embryo transfer.

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“…If it is impossible to perform transcervical embryo transfer with a severely stenotic cervical opening, a transmyometrial embryo transfer under ultrasound guidance can be performed. [57, 58] Gametes or zygotes intrafallopian transfer are also a therapeutic option.…”

Section: Stage Ia2-ib1: Trachelectomymentioning

confidence: 99%

Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma

Kardakis

2012

ISRN Oncology

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Fertility preservation is an important issue for patients in reproductive age with early stage cervical cancer. In view of recent developments, our purpose was to review and discuss available surgical alternatives. A literature search was conducted using PUBMED, including papers between 1980 and December 2011. In patients with stage IA1 cervical cancer, conization is a valid alternative. Patients with stage IA2-IB1 disease can be conservatively treated by radical trachelectomy. This is as well-established conservative approach and appears to be safe and effective in allowing a high chance of conception. Prematurity is the most serious issue in pregnancies following trachelectomy. Less invasive options such as simple trachelectomy or conization seem to be feasible for stages IA2-IB1, but more and better evidence is needed. Neoadjuvant therapy might allow conservative surgery to be performed also in patients with more extensive lesions. Ovarian transposition is important when adjuvant radiation is needed. In conclusion, available literature shows that there are interesting fertility-sparing treatment alternatives to the “golden standard” for the management of early cervical cancer in young women.

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Successful pregnancy following novel IVF protocol and transmyometrial embryo transfer after radical vaginal trachelectomy

Cited by 16 publications

References 14 publications

Successful tubal blastocyst transfer after laparoscopic cervical cerclage: cesarean delivery of a live very low-birth-weight infant and later hysterectomy for uterine rupture

Successful tubal blastocyst transfer after laparoscopic cervical cerclage: cesarean delivery of a live very low-birth-weight infant and later hysterectomy for uterine rupture

Transmyometrial embryo transfer as a useful method to overcome difficult embryo transfers - a single-center retrospective study

Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma

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