Successful treatment of oral pigmented spots in Chinese subjects with Peutz-Jeghers syndrome using a 755-nm picosecond laser

Zeng, Rong; Wu, Qiujv; Guo, Lanwei; Lin, Tong

doi:10.25259/ijdvl_151_20

Cited by 5 publications

(3 citation statements)

References 5 publications

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“…To date, only one other article has been published treating mucosal lentiginosis in Peutz-Jeghers disease with picosecond 755-nm alexandrite laser. 3 As in our case, significant improvement with over 75% clearance could be achieved after one single session, presenting two patients that required a total of two and one sessions, respectively.…”

Section: Discussionsupporting

confidence: 68%

Picosecond 755‐nm alexandrite laser treatment for oral lentiginosis in Peutz–Jeghers disease

et al. 2022

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We present the case of a 16-year-old boy with Peutz-Jeghers disease with successful treatment of oral lentiginosis with one session of picosecond 755-nm alexandrite laser. To date, only in one other article picosecond laser is used for lentiginosis in Peutz-Jeghers disease. Other therapeutical options include Q-switched 755-nm alexandrite, 1064-nm Nd:YAG, 532-nm KTP-laser, ruby and intense pulsed light, which generally require more sessions, are less pigmentselective and have overall worse results than picosecond laser treatment.

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Section: Discussionsupporting

confidence: 68%

Picosecond 755‐nm alexandrite laser treatment for oral lentiginosis in Peutz–Jeghers disease

et al. 2022

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“…While non‐ablative lasers have been integrated as an important tool for the treatment of cutaneous pigmentation, only few studies examined their use in treating intra‐oral pigmentation mainly focusing on the 755‐nm alexandrite Q‐switched and Pico laser 17–20 …”

Section: Discussionmentioning

confidence: 99%

“…While non-ablative lasers have been integrated as an important tool for the treatment of cutaneous pigmentation, only few studies examined their use in treating intra-oral pigmentation mainly focusing on the 755-nm alexandrite Q-switched and Pico laser. [17][18][19][20] Another laser examined for this purpose is the Q-switched Nd:YAG 532-nm laser with a recent study demonstrating favorable results in 10 patients with gingival hyperpigmentation after 1-4 treatment sessions. 21 The use of Q-switched ruby laser, although having the highest affinity to melanin, has only been published in few case reports describing successful treatment of pigmented fungiform papillae of the tongue.…”

Section: Discussionmentioning

confidence: 99%

Q‐switched ruby laser is safe and effective in treating primary gingival hyperpigmentation

Noyman

Kornowski²,

Slodownik

et al. 2023

J of Cosmetic Dermatology

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Oral mucosal hyperpigmentation refers to the intraoral deep-purple, brown or black patch that most commonly affects the gingival surface. 1 Different pathological conditions are associated with oral mucosal hyperpigmentation: genodermatoses including Peutze Jeghers syndrome, endocrinopathies such as Addison's disease and acromegaly, post-inflammatory hyperpigmentation, drug-induced pigmentation (e.g., minocycline, zidovudine, chlorpromazine), heavy metal depositions (e.g., lead, bismuth, mercury) and Amalgam tattoo, to name a few. 2 Physiologic (primary) hyperpigmentation of the oral mucosa is a benign condition that results from increased melanin production. It

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Cancer Risk of Peutz–Jeghers Syndrome and Treatment Experience: A Chinese Medical Center

2023

Clin Colon Rectal Surg

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Peutz–Jeghers syndrome (PJS), also known as hereditary mucocutaneous pigmented gastrointestinal polyposis, is a clinically rare autosomal dominant genetic disease, which falls into the category of hereditary colorectal cancer. There are ∼7,000 new cases of PJS in China every year, and 170,000 PJS patients may survive for a long time in society. PJS polyps are characterized by an early age of onset, difficult diagnosis and treatment, and easy recurrence. With repeated growth, polyps can lead to serious complications such as intestinal obstruction, intussusception, gastrointestinal bleeding, and cancerization, which cause serious clinical problems. Due to repeated hospitalization and endoscopic follow-up, PJS patients and their families suffer from great physical and mental pain and economic burden. With the in-depth understanding of PJS and the development and popularization of endoscopic techniques in the past decade, an integrated treatment modality based on endoscopy plus surgery has gradually become the preferred treatment in most hospitals, which greatly improves the quality of life of PJS patients. However, there is still a lack of effective drug prevention and cure means. In this paper, the current clinical treatment means for PJS polyps were summarized by literature review combined with the treatment experience of our medical center, with a focus on their clinical diagnosis, treatment, and cancer risk.

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Successful treatment of oral pigmented spots in Chinese subjects with Peutz-Jeghers syndrome using a 755-nm picosecond laser

Cited by 5 publications

References 5 publications

Picosecond 755‐nm alexandrite laser treatment for oral lentiginosis in Peutz–Jeghers disease

Picosecond 755‐nm alexandrite laser treatment for oral lentiginosis in Peutz–Jeghers disease

Q‐switched ruby laser is safe and effective in treating primary gingival hyperpigmentation

Cancer Risk of Peutz–Jeghers Syndrome and Treatment Experience: A Chinese Medical Center

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