Coronary artery stenosis and the resulting ischemia of the heart is one of the leading causes of death worldwide. Along with worldwide research on the subject, research is being carried out on the subject in the Nishtar Hospital, Multan. Men are most affected. More morbidity occurs in the last decades of life. However, in some cases, the younger age group is also involved. This is also seen on the top page with higher education and urban settlements. Smoking and alcohol are the main risk factors. This often affects entrepreneurs and service owners. Cardiologists and treating physicians, as well as the general public, need lifestyle changes to consider early treatment and avoid unwanted complications. Aim: This study was conducted to investigate atherosclerotic events in the coronary arteries of sudden death victims. Methods: Research material consisting of 82 randomly selected cases from a total of 980 autopsies carried out due to sudden death in the period from May 2020 to January 2021 at the Forensic Medicine Department of Sheikh Zayed Hospital, Rahim Yar Khan and Islamic International Medical Collage, Rawalpindi. Information on the date, time and place of death, etc. obtained from the investigating police officer or from accompanying family members. 2. Clear cardiovascular diseases and events and current records were obtained from relatives or family members and accompanying police officers. 3. Sociodemographic data was obtained from relatives of the victim. The autopsy and histopathological findings were recorded. The cause of death was determined and the collected data were subjected to statistical analysis. Results: The incidence of coronary stenosis was found in 47 out of 82 cases. In this study, the highest number of cases was recorded in the age groups 17 and 14, and 61-70 and 51-60 years, respectively. Men outnumbered 39 cases and females 8 cases. The youngest participant was a 24-year-old man and the oldest was a 78-year-old woman. Conclusion: The study showed an unexpectedly high incidence of coronary stenosis in this region. Although the incidence is higher in men than in women, it is alarming for both sexes. Cardiologists and treating physicians, as well as the general public, need to change their lifestyle, consider early treatment, avoid unwanted complications, and raise awareness about the disease. Key words: Coronary artery stenosis, Men, Smoking and Alcohol, Businessmen