Sulfonated nanocellulose beads as potential immunosorbents

Rocha, Igor; Ferraz, Natalia; Mihranyan, Albert; Strömme, Maria; Lindh, Jonas

doi:10.1007/s10570-018-1661-2

Cited by 31 publications

(22 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cladophora nanocellulose was converted into DAC beads following the procedure developed by Lindh et al [ 50 ], where extensive periodate oxidation of the nanocellulose leads to spontaneous bead formation, followed by sulfonation and reduction as previously described [ 18 ]. Briefly, DAC beads were first prepared by a one-pot periodate oxidation of the nanocellulose material in an aqueous acetate buffer for 240 h at room temperature with constant magnetic stirring, converting all 2,3-hydroxyl groups to aldehydes.…”

Section: Methodsmentioning

confidence: 99%

“…Our group has recently reported the synthesis of sulfonated cellulose beads prepared from Cladophora nanocellulose [ 18 ]. Nanocellulose from Cladophora green algae is a very versatile material that presents an entangled fibrous web structure, high specific surface area, high degree of crystallinity, and excellent mechanical and rheological properties [ 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…The sulfonated Cladophora nanocellulose beads present properties such as high surface area, high degree of oxidation, spherical shape, and the possibility of tailoring the porosity, making them interesting candidates for the development of immunosorbent platforms, including their use in extracorporeal blood treatments [ 18 ]. Also, the presence of sulfonate groups in the polysaccharide chain may modulate the thrombogenic properties of the Cladophora nanocellulose.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Blood Compatibility of Sulfonated Cladophora Nanocellulose Beads

et al. 2018

Self Cite

View full text Add to dashboard Cite

Sulfonated cellulose beads were prepared by oxidation of Cladophora nanocellulose to 2,3-dialdehyde cellulose followed by sulfonation using bisulfite. The physicochemical properties of the sulfonated beads, i.e., high surface area, high degree of oxidation, spherical shape, and the possibility of tailoring the porosity, make them interesting candidates for the development of immunosorbent platforms, including their application in extracorporeal blood treatments. A desired property for materials used in such applications is blood compatibility; therefore in the present work, we investigate the hemocompatibility of the sulfonated cellulose beads using an in vitro whole blood model. Complement system activation (C3a and sC5b-9 levels), coagulation activation (thrombin-antithrombin (TAT) levels) and hemolysis were evaluated after whole blood contact with the sulfonated beads and the results were compared with the values obtained with the unmodified Cladophora nanocellulose. Results showed that neither of the cellulosic materials presented hemolytic activity. A marked decrease in TAT levels was observed after blood contact with the sulfonated beads, compared with Cladophora nanocellulose. However, the chemical modification did not promote an improvement in Cladophora nanocellulose hemocompatibility in terms of complement system activation. Even though the sulfonated beads presented a significant reduction in pro-coagulant activity compared with the unmodified material, further modification strategies need to be investigated to control the complement activation by the cellulosic materials.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Blood Compatibility of Sulfonated Cladophora Nanocellulose Beads

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…Sulfonated cellulose is a potential immunosorbent material (Rocha et al 2018) and green flocculation agent for mineral particles (Liimatainen et al 2013). Sulfonated cellulose film has a potential application as a separator membrane in lithium-ion batteries (Thiangtham et al 2019).…”

Section: Scheme 1 Sulfonation Of Dacmentioning

confidence: 99%

Preparation of cellulose nanocrystals via successive periodate and bisulfite oxidation and mechanical and hydrophilic properties of the films

Wang¹,

Li²,

Zeng³

et al. 2021

BioRes

View full text Add to dashboard Cite

Microcrystalline cellulose was oxidized via periodate followed by sulfonation. The sulfonated cellulose nanocrystals were obtained through centrifugation, dialysis, and sonication. The sulfonated cellulose nanocrystals were rod-like and had an average length of 140 nm to 153 nm and an average width of 8 to 10 nm. The Fourier transform infrared profiles and polyelectrate titration demonstrated successful introduction of the sulfonated groups into the cellulose nanocrystals. The sulfonated cellulose nanocrystals had a higher crystallinity index than dialdehyde cellulose. The thin films fabricated via the casting of the sulfonated cellulose nanocrystals suspensions were highly hydrophilic.

show abstract

“…Chemical treatments are used to isolate cellulose fibres to generate nanocellulose. Existing chemical pretreatment techniques include acid hydrolysis [ 69 ], carboxylation [ 70 ], carboxymethylation [ 71 ], quaternization [ 72 ], sulphonation [ 73 ], ionic liquid [ 74 ], and solvent-assisted pretreatments [ 75 ].…”

Section: Reviewmentioning

confidence: 99%

Nanocellulose: Recent advances and its prospects in environmental remediation

Shak¹,

Pang²,

Mah³

2018

Beilstein J. Nanotechnol.

229

127

View full text Add to dashboard Cite

Among many other sustainable functional nanomaterials, nanocellulose is drawing increasing interest for use in environmental remediation technologies due to its numerous unique properties and functionalities. Nanocellulose is usually derived from the disintegration of naturally occurring polymers or produced by the action of bacteria. In this review, some invigorating perspectives on the challenges, future direction, and updates on the most relevant uses of nanocellulose in environmental remediation are discussed. The reported applications and properties of nanocellulose as an adsorbent, photocatalyst, flocculant, and membrane are reviewed in particular. However, additional effort will be required to implement and commercialize nanocellulose as a viable nanomaterial for remediation technologies. In this regard, the main challenges and limitations in working with nanocellulose-based materials are identified in an effort to improve the development and efficient use of nanocellulose in environmental remediation.

show abstract

Sulfonated nanocellulose beads as potential immunosorbents

Cited by 31 publications

References 44 publications

Blood Compatibility of Sulfonated Cladophora Nanocellulose Beads

Blood Compatibility of Sulfonated Cladophora Nanocellulose Beads

Preparation of cellulose nanocrystals via successive periodate and bisulfite oxidation and mechanical and hydrophilic properties of the films

Nanocellulose: Recent advances and its prospects in environmental remediation

Contact Info

Product

Resources

About