Sumac Silver Novel Biodegradable Nano Composite for  Bio-Medical Application: Antibacterial Activity

Ghorbani, Parisa; Soltani, Mohammad Reza; Tabrizi, Masoud Homayouni; Namvar, Farideh; Azizi, Susan; Mohammad, Rosfarizan; Moghaddam, Amin Boroumand

doi:10.3390/molecules200712946

Cited by 30 publications

(22 citation statements)

References 31 publications

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“…Therefore it can be supposed that these compounds like flavonoid, tannins and other phenolic compounds acts as the capping agent in the formation of gold nanoparticles which similarly help in the stabilization of nanoparticles at physiological condition 32 . Similar result was also reported in our pervious study for synthesizing of silver nanoparticles 33 .…”

Section: Ftir Analysissupporting

confidence: 92%

Green Synthesis of Gold Nanoparticles Using Sumac Aqueous Extract and Their Antioxidant Activity

et al. 2016

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Green synthesis of nanoparticles which have eco-friendly favourable solvent systems and environmentally reducing agents is of excessive importance. In this paper, we aimed to develop environmentally friendly, rapid and simple producer for the synthesis gold nanoparticles (Au-NPs) using aqueous extract of sumac as reducing agents for gold ions as well capping agent for the bioformed Au-NPs. The bio-synthesized Au-NPs were characterized by the UV-visible spectroscopy, FTIR, TEM, and zeta-potential measurements. The surface plasmon resonance band centred at 520 nm for Au-NPs was characterized by UV-visible spectrophotometer. The probable bio-molecules are polyphenols may responsible for reduction of gold ions were recognized through FT-IR. The TEM result shows the bioformed Au-NPs are spherical in shapes with the mean size of 20.83 ±4.4 nm. The capping of anionic bio-molecules on the surface of Au-NPs was confirmed by zeta potential assessment (-25.3 mV) and is responsible for the electrostatic stability. In vitro antioxidant activity studies showed that DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2, 2'-azino-bis 3-ethylbenzthiazoline-6-sulfonic acid) activities increased in a dose dependent manner. The bio-synthesized nanoparticles can potentially useful in pharmaceutical and biomedical applications.

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Section: Ftir Analysissupporting

confidence: 92%

Green Synthesis of Gold Nanoparticles Using Sumac Aqueous Extract and Their Antioxidant Activity

et al. 2016

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“…This pattern clearly revealed that the AgNPs by green method are nanocrystalline in nature. In present paper, the results are in agreement with different reports that investigated the cubic nature of phyto-synthesised AgNPs [23].…”

Section: Synthesis and Characterisation Of Agnpssupporting

confidence: 93%

Antioxidant, antibacterial and anticancer properties of phyto‐synthesisedArtemisia quttensisPodlech extract mediated AgNPs

Ghanbar¹,

Mirzaie

Ashrafi³

et al. 2017

IET nanobiotechnol.

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The focus of this study is on a rapid and cost-effective approach for the synthesis of silver nanoparticles (AgNPs) using Podlech aerial parts extract and assessment of their antioxidant, antibacterial and anticancer activities. The prepared AgNPs were determined by ultraviolet-visible spectroscopy, X-ray diffraction, Fourier transform infra-red spectroscopy, transmission electron microscopy, scanning electron microscopy, energy-dispersive spectroscopy, and dynamic light scattering and zeta-potential analysis. The AgNPs and extract were evaluated for their antiradical scavenging activity by 2, 2-diphenyl, 1-picryl hydrazyl assay and anticancer activity against colon cancer (human colorectal adenocarcinoma cell line 29) compared with normal human embryonic kidney (HEK293) cells. Also, the prepared AgNPs were studied for its antibacterial activity. The AgNPs revealed a higher antioxidant activity compared with extract alone. The phyto-synthesised AgNPs and extract showed a dose-response cytotoxicity effect against HT29 and HEK293 cells. As evidenced by Annexin V/propidium iodide staining, the number of apoptotic HT29 cells was significantly enhanced, following treatment with AgNPs as compared with untreated cells. Besides, the antibacterial property of the AgNPs indicated a significant effect against the selected pathogenic bacteria. These present obtained results show the potential applications of phyto-synthesised AgNPs using aerial parts extract.

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“…The range of microbicidal properties of Ag NPs is wider than that of antibiotics, and the appearance of resistant bacteria such as MRSA is rare in Ag NP-based materials [115]. The combination of various materials with Ag NP-based materials has been studied [116,117,118,119]. The production of wound dressings and medical catheters coated with Ag NPs has been investigated.…”

Section: Other Medical Applicationsmentioning

confidence: 99%

Synthesis and Application of Silver Nanoparticles (Ag NPs) for the Prevention of Infection in Healthcare Workers

Nakamura

Sato

et al. 2019

IJMS

211

115

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Silver is easily available and is known to have microbicidal effect; moreover, it does not impose any adverse effects on the human body. The microbicidal effect is mainly due to silver ions, which have a wide antibacterial spectrum. Furthermore, the development of multidrug-resistant bacteria, as in the case of antibiotics, is less likely. Silver ions bind to halide ions, such as chloride, and precipitate; therefore, when used directly, their microbicidal activity is shortened. To overcome this issue, silver nanoparticles (Ag NPs) have been recently synthesized and frequently used as microbicidal agents that release silver ions from particle surface. Depending on the specific surface area of the nanoparticles, silver ions are released with high efficiency. In addition to their bactericidal activity, small Ag NPs (<10 nm in diameter) affect viruses although the microbicidal effect of silver mass is weak. Because of their characteristics, Ag NPs are useful countermeasures against infectious diseases, which constitute a major issue in the medical field. Thus, medical tools coated with Ag NPs are being developed. This review outlines the synthesis and utilization of Ag NPs in the medical field, focusing on environment-friendly synthesis and the suppression of infections in healthcare workers (HCWs).

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Sumac Silver Novel Biodegradable Nano Composite for Bio-Medical Application: Antibacterial Activity

Cited by 30 publications

References 31 publications

Green Synthesis of Gold Nanoparticles Using Sumac Aqueous Extract and Their Antioxidant Activity

Green Synthesis of Gold Nanoparticles Using Sumac Aqueous Extract and Their Antioxidant Activity

Antioxidant, antibacterial and anticancer properties of phyto‐synthesisedArtemisia quttensisPodlech extract mediated AgNPs

Synthesis and Application of Silver Nanoparticles (Ag NPs) for the Prevention of Infection in Healthcare Workers

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