Sun Protection Factor Determination Studies of Some Sunscreen Formulations Used in Cosmetics for Their Selection

Khan, Masheer Ahmed

doi:10.22270/jddt.v8i5-s.1924

Cited by 19 publications

(10 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This Previous studies on cinnamic acid have shown that this compound can be used as a photoprotective agent [10], and PMCA has the potential as an antibacterial against E. coli [3]. In addition, cinnamic acid derivatives also showed activity as a sunscreen [11][12][13]. So, it can be expected that PMCA also has better activity than these compounds.…”

Section: Introductionmentioning

confidence: 91%

Synthesis of PMCA (P-Methoxy Cinnamic Acid) using Perkin Reaction and Its Activity as Photo Protective and Antifungal Agent

Purwaningsih¹,

Indriyanti²,

Masduqi

2022

JKPK

View full text Add to dashboard Cite

This study aimed to synthesize p-methoxy cinnamic acid through the Perkin reaction and to determine its activity as a photoprotective and antifungal agent against Candida albicans. The PMCA compound was synthesized by reacting p-methoxy benzaldehyde with acetic anhydride using a sodium acetate catalyst in a sonicator at 50oC for 60 minutes. The synthesized was a white precipitate with a % yield of 2.09% and a melting point of 172-175oC. ATR-FTIR identified this compound with several functional groups, C=O, OH carboxylic acid, para-substituted benzene, and C=C. Analysis by GC-MS showed a single peak at a retention time of 11.710 minutes with m/z 178. Characterization of this compound by 1H-NMR spectrometry showed several chemical shifts showing the presence of OH groups of carboxylic acids, C=C groups, aromatic benzene groups, and methoxy. The results of this characterization indicated that the synthesis product was PMCA. The antioxidant activity of PMCA using the DPPH radical gave IC50 at a concentration of 352.6138 ppm. In vitro sunscreen activity against PMCA compounds provided high protection at a concentration of 30 ppm with SPF 32,505. The antifungal activity against Candida albicans showed inhibition zones of 0.257cm± 0.044, 1.397cm± 0.093, and 1.533cm± 0.111, respectively at concentrations of 5%, 10%, and 15%. The PMCA compounds can be synthesized through the Perkin reaction assisted by ultrasonic waves and can potentially be photoprotective and antifungal agents.

show abstract

Section: Introductionmentioning

confidence: 91%

Synthesis of PMCA (P-Methoxy Cinnamic Acid) using Perkin Reaction and Its Activity as Photo Protective and Antifungal Agent

Purwaningsih¹,

Indriyanti²,

Masduqi

2022

JKPK

View full text Add to dashboard Cite

show abstract

“…Where, CF = correction factor (10), EE (𝜆 ) = erythmogenic effect of radiation with wavelength 𝜆 , Abs (𝜆 ) = spectrophotometric absorbance values at wavelength 𝜆 . Table 1 shows the values of the EE (𝜆 ) x I constants (Khan, 2018) .…”

Section: Spf Test Using Uv Spectrophotometrymentioning

confidence: 99%

Photoprotective and Antioxidant Potential of Indonesia’s Klanceng Honey Beehive Waste

Purwaningsih

Masduqi

Indriyanti

et al. 2023

Sci. Technol. Indones

View full text Add to dashboard Cite

A byproduct of the honey processing called Klanceng honey beehive waste is said to still contain secondary metabolites that are beneficial to health. The objective of this research was to assess the photoprotective properties of an ethanol extract, n-hexane fraction, and ethyl acetate fraction obtained from the waste of an Indonesian Klanceng honey beehive that originated in Magelang. The DPPH free radical technique was applied to quantify antioxidant properties, and the Mansur equation’s SPF value was used to calculate photoprotective activity. The analysis of the data revealed that the IC50 values for the ethanol extract, n-hexane fraction, and ethyl acetate fraction were, respectively, 470.2935±0.9249, 207.1869± 2.6510, and 216.4892±0.8349. The ethanol extract, n-hexane fraction, and ethyl acetate fraction of the samples had SPF values of 3.872, 3.529, and 9.358, respectively. The ethyl acetate fraction, as opposed to the ethanol extract and the n-hexane fraction, has greater potential as a photoprotective agent as a result.

show abstract

“…Where the prepared composite films were scanned between 290 and 320 nm by using a UV spectrophotometer and the obtained absorbance values were multiplied with the respective EE (λ) and I (λ) values (constant value as shown in Table 1). 26 Then, their summation was taken and multiplied with the correction factor (10).…”

Section: Density Of the Cross-linked Composite Filmmentioning

confidence: 99%

Fabrication and Determination of the Sun Protection Factor and Ultraviolet Protection Factor for Piscean Collagen/Bischalcone Derivative (B1) Composite Films with Wide-Range UV Shielding

2022

View full text Add to dashboard Cite

The present study investigates the development of distinct UV-A and UV-B radiation filtering materials through the introduction of a heterocyclic bischalcone derivative [(3,5-bis{[4-(methylsulfanyl)phenyl]methylidene}piperidin-4-one] ( B1 ) into the matrix of PVA/Piscean collagen blend films (1:1) prepared through the solution casting method and characterized. The dopant concentration varied from 0.25 to 4%. The scanning electron microscopy images showed the rough surface due to the uniform dispersion of dopant B1 . The addition of different concentrations of B1 altered the mechanical strength with a proportional increase in Young’s modulus (146–317 MPa), tensile strength (23.3–39.21 MPa), and decrease in its elongation at break (158.8–105.2%). As the dopant B1 belongs to the bischalcone class of compounds which absorb in the UV–vis region (370 nm λ max ) due to the α, β unsaturated keto group, it was selected for doping. Dopant concentration-dependent increase in density was observed in films (31–162 mg/cm 3 ). The bathochromic shift in UV absorption from 370 to 390 nm for λ max as well as hyperchromism was evidenced with proportional increase in the concentration of B1 , indicating its capacity to block UV rays. On determining the UV filtering ability for all the prepared films, the one with 4% dopant showed a higher sun protection factor (SPF) with a value of 27.53 and ultraviolet protection factor (UPF) with a value of 58.23. In addition, the degradation of supercoiled PBR322 DNA on UV irradiation was effectively inhibited by these films with a dopant concentration of 0.5–4.0%, which might cause less harm to the skin. The inferences of the experiments would indicate the use of these water-insoluble films as UV blocking potential materials with a merit of SPF and UPF characteristics.

show abstract

Sun Protection Factor Determination Studies of Some Sunscreen Formulations Used in Cosmetics for Their Selection

Cited by 19 publications

References 5 publications

Synthesis of PMCA (P-Methoxy Cinnamic Acid) using Perkin Reaction and Its Activity as Photo Protective and Antifungal Agent

Synthesis of PMCA (P-Methoxy Cinnamic Acid) using Perkin Reaction and Its Activity as Photo Protective and Antifungal Agent

Photoprotective and Antioxidant Potential of Indonesia’s Klanceng Honey Beehive Waste

Fabrication and Determination of the Sun Protection Factor and Ultraviolet Protection Factor for Piscean Collagen/Bischalcone Derivative (B1) Composite Films with Wide-Range UV Shielding

Contact Info

Product

Resources

About