Supercritical fluid extraction and chromatography of steroids with Freon-22

Li, Sam Fong Yau; Ong, Chye Peng; Lee, M.L.; Lee, H.K.

doi:10.1016/s0021-9673(01)89348-1

Cited by 39 publications

(12 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A commercial SFC instrument was used for the analysis of the two compounds considered in this work. This instrument was used because the homemade system lacked a pressure programmer, which precluded the optimization of the analytical conditions; nevertheless, we have successfully used it to analyze steroids (9).…”

Section: Resultsmentioning

confidence: 99%

The extraction of cholesterol from solid and liquid matrices using supercritical CO₂

Ong

et al. 1990

J Microcolumn Separations

View full text Add to dashboard Cite

Abstract. The design and construction of a relatively simple supercritical CO, system capable of extracting compounds from solid and liquid matrices are described. The system consists of a conventional liquid chromatography pump, a cooler, a stainless steel extraction chamber, and a modified collection system. A preliminary evaluation of the extractor is carried out here by using it to extract cholesterol from egg yolk and blood serum. The extracts were analyzed by supercritical fluid chromatography, and the results compared with those obtained by Soxhlet extraction.

show abstract

Section: Resultsmentioning

confidence: 99%

The extraction of cholesterol from solid and liquid matrices using supercritical CO₂

Ong

et al. 1990

J Microcolumn Separations

View full text Add to dashboard Cite

show abstract

“…Various veterinary drugs such as dimenthoprim, hexestrol, diethylstilbestrol, and dienestrol were extracted and identified from the freeze-dried pig's kidney using the online SFE-SFC MS-MS system [150]. The Supercritical Freon-22 having higher extraction efficiency found significantly great extraction with steroid standards [estrone, testosterone, estriol, 17, amethylteste, 17, amethylteste] [151].…”

Section: Steroidsmentioning

confidence: 99%

Super-Critical Fluid: An Overview on Analytical Applications

Kadri

Xavier

Patel

et al. 2021

CGC

View full text Add to dashboard Cite

Abstract:: Super Critical Fluid is the emerging technique that consists of super solvent, which is considered a boon over many other conventional solvents. The main component utilized in it is Carbon Dioxide [CO2], which possesses dual state properties such as effusion through solid and other dissolving materials like liquid which results in unique applications bidden with no limitations. The varying temperature and pressure are the important parameters optimized and thus enhance its solvent properties. Higher Co-efficient of diffusion, reduction in time, higher compressibility, etc., is some of the major advantages of SCF-CO2 over the conventional solvents. Over and above, it is a green approach and a super solvent. Here we have discussed the multifarious applications of the SCF-CO2 extraction in fields and areas extended, but not limited to, Food, Environmental, Analysis, Metal-Cation Extraction, as well as Extractions, Forensics, Pharmaceuticals, Toxins, and Botanical Samples.

show abstract

“…Chlorodifluoromethane (Freon-22) has proven to possess excellent solvation properties for chromatography and sample extraction of polar analytes. 63,64 Trifluoromethane also possesses similar properties, [65][66][67] as does the more ecofriendly tetrafluoroethane (Freon-134a). 68,69 The downside to using these substances as solvents is their limited availability, higher cost and environmental concerns.…”

Section: General Considerations Of Supercritical Fluids Applied To Samentioning

confidence: 99%

Supercritical fluids in medical radioisotope processing and chemistry, Part I: technology, instrumentation and methodology

Ferrieri

2003

Labelled Comp Radiopharmac

View full text Add to dashboard Cite

SummaryAlthough the last two decades has seen a keen interest in using supercritical fluids as media for material processing and chemical reactions owing to their unique physical properties, this technology has been underutilized in medical radioisotope processing and chemistry. The successful application of this technology necessitates not only having a sound knowledge of the physicochemical properties and phenomena occurring within such critical states of matter, but also a clear idea of the tools needed and means for applying them. These topics will be presented under the cover of two parts. Part I will address topics on the general background of supercritical fluid technology, equipment needed, whether for chemistry or separation, and basic techniques to access critical states of matter. Part II will follow in a subsequent volume and is meant to provide a description of applications with cited examples and potential areas for development. The hope is that sufficient interest is stimulated so as to encourage radiochemists to look to alternative technologies of this nature to

show abstract

Supercritical fluid extraction and chromatography of steroids with Freon-22

Cited by 39 publications

References 8 publications

The extraction of cholesterol from solid and liquid matrices using supercritical CO₂

The extraction of cholesterol from solid and liquid matrices using supercritical CO₂

Super-Critical Fluid: An Overview on Analytical Applications

Supercritical fluids in medical radioisotope processing and chemistry, Part I: technology, instrumentation and methodology

Contact Info

Product

Resources

About

Supercritical fluid extraction and chromatography of steroids with Freon-22

Cited by 39 publications

References 8 publications

The extraction of cholesterol from solid and liquid matrices using supercritical CO2

The extraction of cholesterol from solid and liquid matrices using supercritical CO2

Super-Critical Fluid: An Overview on Analytical Applications

Supercritical fluids in medical radioisotope processing and chemistry, Part I: technology, instrumentation and methodology

Contact Info

Product

Resources

About

The extraction of cholesterol from solid and liquid matrices using supercritical CO₂

The extraction of cholesterol from solid and liquid matrices using supercritical CO₂