Superficial Enhanced Fluid Fat Injection (SEFFI) to Correct Volume Defects and Skin Aging of the Face and Periocular Region

Abstract

4 Therapeutic.

Rejuvenation of the deep superior sulcus in the eyelid

“…34 In our opinion, although it is controversial, the retrograde and resistance-free injection under low pressure is the most important. 7,36,37 Therefore, we prefer using relatively large-caliber (23 gauge or larger) needles for this procedure.…”

Autologous fat transfer with SEFFI (superficial enhanced fluid fat injection) technique in periocular reconstruction

“…In the periocular area, fat filling was performed using a retrograde injection technique (to prevent real risk of fat embolism) exerting the least possible pressure. Five cc 0.5 mL SEFFI syringes with 23G needles and 5 cc 0.8 mL SEFFI syringes with 20G needles were used 4 The results were subjectively evaluated both by surgeons and patients using standardized photographic exams (Canon® EOS Rebel T3i with 60 mm lens, Tokyo, Japan) pre-and post-intervention with a minimum follow-up of 6 months. Written consent was obtained from all identifiable patients.…”

“…This technique, SEFFI (superficial enhanced fluid fat injection), uses 0.5 and 0.8 mL micro-cannulas in order to collect fine fat, rich in pluripotent cells. 4 We have expanded the use of SEFFI for periocular rehabilitation with good results.…”

The Development of Facial Lipofilling from a Historical Point of View

“…96 On the other hand, multiple research groups did not show any difference in adipocyte viability nor ASCs differentiation potential of lipoaspirate obtained by different diameter size harvesting cannulas, such as, 0.3, 0.5, 0.8, and 2.0 mm. [98][99][100] Another research group observed no significant differences in vitro between a 3-mm diameter harvesting cannula and a 2-mm diameter harvesting cannula (microfat harvesting) in terms of cell yield and viability. 101 Yet, ASCs from microharvested lipoaspirates adhered significantly faster to collagen-elastin matrices which might be beneficial for tissue engineering.…”