Superficial siderosis: a case report and review of the literature

Abstract

Iron chelating agents.

Superficial siderosis associated with aceruloplasminemia. Case report

“…Both are well-known disorders of iron accumulation in the brain, but, to our best knowledge, no previous report has described the coincidence of Finally hemosiderin is made from dense ferritin, and is deposited in subpial, subependymal and leptomeningeal regions. Several diseases including brain tumors, head or back trauma, and arteriovenous malformations, and neurosurgical procedures are reported as the underlying etiologies of SS [3]. Through the introduction of MRI sequences sensitive to susceptibility change such as T2*WI and SWI, asymptomatic SS is often found [3].…”

“…Several diseases including brain tumors, head or back trauma, and arteriovenous malformations, and neurosurgical procedures are reported as the underlying etiologies of SS [3]. Through the introduction of MRI sequences sensitive to susceptibility change such as T2*WI and SWI, asymptomatic SS is often found [3].…”

“…SS usually presents with hearing loss, ataxia, and pyramidal tract signs. Magnetic resonance imaging (MRI) scans, particularly T2*-weighted imaging (T2*WI) is very useful for the diagnosis of SS [3].…”

Superficial Siderosis of the CNS and Otoneurological Manifestations

“…Superficial siderosis is a pathological condition in which hemosiderin-a product of breakdown of blood, is deposited in the subpial layer of CNS [1] leading to progressive and irreversible neurological deficits like sensorineural hearing loss, cerebellar ataxia and myelopathy. The hemosiderin deposition is seen in those parts of the CNS that are adjacent to CSF [7].…”

“…Superficial siderosis of CNS occurs due to recurrent bleeding in the subarachnoid and subpial spaces [1]. It is an uncommon and potentially debilitating disorder.…”