Superior macular sparing in central retinal artery occlusion due to sickle cell anaemia

Sanghvi, C; Laude, Augustinus; Smith, Amy; Dodd, C L

doi:10.1038/sj.eye.6700684

Cited by 5 publications

(2 citation statements)

References 5 publications

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“…In retina, the sickled red blood cells obstruct the retinal vessels leading to reduced blood flow and retinal vascular occlusion. There are only a few published reports of retinal artery occlusion associated with SCD [ 5 - 7 ]. Treatment experience of CRAO with SCD is even more limited.…”

Section: Discussionmentioning

confidence: 99%

“…In these cases, exchange transfusion should be considered first in order to restore vascular perfusion [ 6 ]. Hydroxyurea may be recommended for prophylactic treatment to prevent systemic crises [ 5 ]. The alternatives for the treatment of CRAO in SCD consist of pharmacological and mechanical reduction of ocular pressure, HBO therapy, ocular massage, and direct thrombolysis, however their benefits are not well proven [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

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Hyperbaric oxygen therapy in combination with systemic treatment of sickle cell disease presenting as central retinal artery occlusion: a case report

2014

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IntroductionWe describe hyperbaric oxygen therapy for the treatment of central retinal artery occlusion in a young adult with sickle cell disease.Case presentationA 25-year-old Turkish man with a history of sickle cell disease developed sudden painless loss of vision in the left eye and was hospitalized for diagnosis and treatment. Central retinal artery occlusion was diagnosed with retinal whitening, cherry red spot, and delayed arteriovenous transit on fluorescein angiography. He underwent exchange transfusion and hyperbaric oxygen therapy. In the following three months, his visual acuity improved to 20/30.ConclusionsIn this present case with sickle cell disease, the visual acuity improved with hyperbaric oxygen therapy in addition to systemic therapy. The result of our case suggests that hyperbaric oxygen therapy may be beneficial in the treatment of central retinal artery occlusion.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Hyperbaric oxygen therapy in combination with systemic treatment of sickle cell disease presenting as central retinal artery occlusion: a case report

2014

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Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Liem

Calamaras

Chhabra

et al. 2008

Pediatric Blood & Cancer

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Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.

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Central Retinal Artery Occlusion

Hayreh¹

2014

Ocular Vascular Occlusive Disorders

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Superior macular sparing in central retinal artery occlusion due to sickle cell anaemia

Cited by 5 publications

References 5 publications

Hyperbaric oxygen therapy in combination with systemic treatment of sickle cell disease presenting as central retinal artery occlusion: a case report

Hyperbaric oxygen therapy in combination with systemic treatment of sickle cell disease presenting as central retinal artery occlusion: a case report

Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Central Retinal Artery Occlusion

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