Superoxide targeted “turn-on” fluorescence sensing enabled by a diselenide based quinoline probe and its in vitro anticancer activity in cancer cells

Abstract

First organoselenium-based quinoline probe was successfully synthesized and characterized by common spectroscopic techniques. The probe was found to be selective and sensitive for superoxide detection over other reactive oxygen species...

Recent progress of organic fluorescent molecules for bioimaging applications: cancer-relevant biomarkers

“…A significantly high IC 50 value (65.21 mM) indicated that the probe had better biocompatibility with normal cells (MDCK) and that it would be a compelling drug for the treatment of lung cancer cells. 98…”

“…The reaction mechanism of the probe with O 2 À (grey: weak fluorescence signal; green: emitted yellow-green fluorescence), and microscopic photographs in MKDC cells in control group (A) and treated with the probe at concentrations of 1 mM (B). Reproduced with permission 98. Copyright 2023, Royal Society of Chemistry.…”