Supplementary Figure 1 from Constitutively Active ErbB2 Regulates Cisplatin-Induced Cell Death in Breast Cancer Cells via Pro- and Antiapoptotic Mechanisms
Abstract:<p>Supplementary figure 1: Effects of cisplatin treatment on expression of ΔNErbB2 and NHE1, and subcellular localization of cytochrome c. MCF-7 vector (V) and ΔNErbB2 (ΔN) cells were washed free of tetracycline 48 h before the experiment, and exposed to cisplatin (25 μM) or control conditions for 18 h. Cells were subsequently processed for immunoblotting (A), immunofluorescence analysis (B) or cell surface biotinylation (C-D). A. ΔNErbB2, top panel shows representative immunoblots, lower panel show… Show more
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