Supplementary Figures 1 - 5, Table 1 from COX-2 Drives Metastatic Breast Cells from Brain Lesions into the Cerebrospinal Fluid and Systemic Circulation

Abstract

<p>PDF file - 338KB, Figure S1. COX-2 is overexpressed in MDA-MB-231 cells. Figure S2. Celecoxib inhibits the invasion and migration capacity of breast cancer cells in vitro. Figure S3. Celecoxib inhibits the migration of breast cancer cells into the cerebrospinal fluid. Figure S4. Enumerating human breast cancer cells in mouse blood using the CellSearch system. Figure S5. Changes in CTC and CSFTC counts as a function of changes in neurological or systemic clinical symptoms of disease. Table S1. Receptor status of enrolled breast cancer patients.</p>