Supplementary Methods, Figures 1 - 3, Tables 1 - 4 from Deregulation of a Hox Protein Regulatory Network Spanning Prostate Cancer Initiation and Progression

Abstract

<p>PDF file, 315KB, Supplemental Figure 1: Validation of differential Meis1 and Meis2 expression between Prostate and Seminal Vesicle Epithelial Cells. Supplemental Figure 2: Gene expression profiles from 181 prostatectomy specimens of patients (Taylor dataset) using the PAM (Prediction Analysis for Microarrays) algorithm to stratify patients into two groups based on changes in expression of Meis1, Meis2, Pbx1, HoxA9, HoxB7. Supplemental Figure 3: Meis biomodule network analysis. Supplemental Methods: qPCR Analyses of Meis1 and Meis2. Supplemental Table 1: Historical datasets used in the analyses. Supplemental Table 2: Prostate epithelial cell (PrEC) versus seminal epithelial cell (SVEC) culture differentially expressed genes. Supplemental Table 3: Functional Annotation of the Prostate versus Seminal Vesicle Epithelium Signature. Supplementary Table 4: Univariate and Multivariate Cox Regression.</p>