Supporting dataset on the validation and verification of the analytical method for the biomonitoring of 360 toxicologically relevant pollutants in whole blood

Abstract

The dataset presented in this article supports “Micro QuEChERS-based method for the simultaneous biomonitoring in whole blood of 360 toxicologically relevant pollutants for wildlife” (Rial-Berriel et al., 2020). The supplementary data are: (1) Detailed validation data of the LC-MS/MS and GC-MS/MS methods for the quantification of 360 chemicals covering bias and precision (intra- and inter-day variability) for retention times, linearity, and limits of quantification. (2) Graphical data of the matrix effects on the quantification of all of the analytes. (3) Individual data of the 51 chemicals detected in real whole blood samples from two raptor species: 36 barn owls ( Tyto alba ) and 112 common kestrels ( Falco tinnunculus ).

A Method Scope Extension for the Simultaneous Analysis of POPs, Current-Use and Banned Pesticides, Rodenticides, and Pharmaceuticals in Liver. Application to Food Safety and Biomonitoring

“…Overall, in quantitative terms, the group of organochlorine pesticides was the most abundant (Figure 2), and the group of persistent and semi-persistent organic pollutants accounted for more than 92% of the total concentration of pollutants detected in the livers of wild birds sampled in the Canary Islands very recently (September 2020-May 2021). This reflects, once again, that contamination by these compounds, in particular organochlorine insecticides, is still very prevalent in the Canary Islands, as has been reported for wildlife in this region [28,[45][46][47]. As indicated in the previous section, there is a large literature body documenting the high levels of contamination by organochlorine pesticides in this region [48][49][50], which also translates into high levels in the biota that inhabit the archipelago.…”

“…pled in the Canary Islands very recently (September 2020-May 2021). This reflects, once again, that contamination by these compounds, in particular organochlorine insecticides, is still very prevalent in the Canary Islands, as has been reported for wildlife in this region [28,[45][46][47]. As indicated in the previous section, there is a large literature body documenting the high levels of contamination by organochlorine pesticides in this region [48][49][50], which also translates into high levels in the biota that inhabit the archipelago.…”

“…In our previous research we optimized and validated a multi-residue method for the analysis of 360 substances (pharmaceuticals, pesticides, rodenticides, and POPs) in blood for biomonitoring purposes [16,28]. Therefore, this is not an ex-novo methodological development, but an extension of the scope of our previously published method to include a new matrix, the liver.…”

“…The first part of this research consists of a validation of a method scope extension. The original method was developed for whole blood [16,28], and now it has been validated for liver matrix. But more interesting, probably, is the second part of our paper, in which we present and discuss the results of the application of this methodology to the two fields described.…”

Epidemiology of Animal Poisonings in the Canary Islands (Spain) during the Period 2014–2021

“…This law names the Toxicology laboratory of the University of Las Palmas de Gran Canaria as the reference laboratory for the official investigation of poisoning incidents in this region, as it had been in charge of the official investigation of such events since January 2014 [4,34]. Consequently, our laboratory began to receive the totality of the samples generated in the incidents investigated by the environmental police and has been developing all the necessary methodology to perform the most complete search possible of all toxic substances that usually affect or could affect the health of wildlife and domestic fauna [35][36][37].…”