Suppression of the hyperosmolarity response after cataract surgery

Kawasaki, Kazuo; Yonemura, D; Yanagida, Takashi; Segawa, Yasunori; Wakabayashi, K.; Mukoh, S; Ishida, Hitomi; Fujii, Shigeru; Takahara, Yoshikazu

doi:10.1007/bf00220228

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Prospects For a True Rpe Test: Nonphotic Responses1

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1991

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“…This would have been an extremely valuable differential for diagnostic purposes, but later studies [39][40][41][42][43] have blurred the distinction. The hyperosmolarity response appears to be abnormal in a broad range of RPE disorders, including retinitis pigmentosa, Stargardt's disease, butterfly dystrophy, retinal detachment, and pigmented paravenous atrophy.…”

Section: Prospects For a True Rpe Test: Nonphotic Responsesmentioning

confidence: 99%

Clinical electrophysiology of the retinal pigment epithelium

Marmor

1991

Doc Ophthalmol

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There is no ideal electrophysiological test for retinal pigment epithelial (RPE) function. The light-induced responses (EOG, c-wave, fast oscillation) that require photoreception are not pure RPE signals, and even the widely-used EOG has not been associated with any specific physiological disturbance of the RPE or retina. The discovery of non-photic RPE responses (hyperosmolarity, acetazolamide and bicarbonate) has enhanced the possibility of finding tissue-specific RPE tests, but these responses have yet to be correlated with specific RPE functional activity or pathology. We may face a dilemma in our search for RPE tests, insofar as electrophysiology measures membrane changes, but RPE membrane activity is related only indirectly to many functions of the RPE cell. These concerns notwithstanding, RPE electrophysiology can be a valuable clinical tool if one accounts for the physiological limitations and assets of the procedures.

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Section: Prospects For a True Rpe Test: Nonphotic Responsesmentioning

confidence: 99%

Clinical electrophysiology of the retinal pigment epithelium

Marmor

1991

Doc Ophthalmol

View full text Add to dashboard Cite

show abstract

Suppression of the hyperosmolarity response after cataract surgery

Cited by 1 publication

References 7 publications

Clinical electrophysiology of the retinal pigment epithelium

Clinical electrophysiology of the retinal pigment epithelium

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