Supramolecular architectures with pyridine-amide based ligands: discrete molecular assemblies and their applications

Abstract

Recent years have seen a surge of interest in supramolecular architectures with the focus shifting towards generating discrete molecular assemblies and factors controlling their formation. Such molecular assemblies offer a wide range of applications which are often architecture-dependent. To construct such assemblies, nitrogen-donor ligands have been intensively employed to generate an assorted variety of topologies. Out of various nitrogen-donor ligands, pyridine-amide based ligands stand out as they not only offer structural flexibility and their ability to adjust to the geometrical requirements of a metal ion but also offer dual functional groups: pyridine and amide. The present perspective will focus on recent developments in the design of discrete supramolecular assemblies utilizing pyridine-amide based ligands with a specific stress on the architectural aspects and subsequent applications of designed molecular assemblies.

Cell permeable fluorescent colorimetric Schiff base chemoreceptor for detecting F− in aqueous solvent

“…Till date F -detection has been mainly carried out by urea, amide, and imidazolinium based chemoreceptor [32][33][34][35][36]. In recent time Schiff bases have been taken into consideration because Schiff bases are relatively easy to prepare and can be tailored structurally.…”

Self‐Assembled Supramolecular Hetero‐Bimetallacycles for Anticancer Potency by Intracellular Release

“…[1] Wide arrays of molecular architectures with various aesthetically pleasing shapes, sizes, and symmetries have been reported using a coordination-driven directional bonding approach that combines rigid, ligand-capped transition metal acceptors and mono- or multidentate donors bearing O- and N-coordinating sites. [2] Square, planar Pd(II) and Pt(II) organometallic acceptors with pyridyl or nitrogen donor linkers are most extensively used for the design of such metallacyclic structures because of their rigid square-planar coordination environments .…”

Self-assembled metal–organic polyhedra: An overview of various applications

“…In cancer research, discrete metal-based nanostructures are of great interest because of their unique chemical and host-guest properties, which distinguish them from traditional mononuclear metalbased anticancer agents [87][88][89][90]. Nano delivery systems such as polymeric nanoparticles [91,92], gold nanoparticles [93,94], carbon nanotubes [95][96][97], and metal-organic framework [98] have a well-defined cavity, which can be used to encapsulate small molecules by host-guest interactions and have been extensively used for Pt(IV) prodrug delivery.…”