Pillar[n]arene is a novel kind of synthetic supramolecular
macrocyclic host characterized by its particular pillar-shaped structure
consisting of an electron-rich cavity and two finely adjustable rims.
Benefiting from its rigid structure, facile synthesis, ease of functionalization,
and outstanding host–guest chemistry, pillar[n]arene shows great potential for diverse applications. Significantly,
the host–guest recognition of pillar[n]arene
provides a novel approach for chemosensing and imaging. Herein, this
Review critically and comprehensively reviews the applications of
pillar[n]arene-based host–guest recognition
in chemosensing and imaging. The sensing and imaging mechanisms as
well as the unique roles and advantages of pillar[n]arene-based host–guest recognition are summarized. In addition,
preparations of hybrid materials based on pillar[n]arene and inorganic materials are also introduced comprehensively
in the light of chemosensing and imaging. Finally, current challenges
and perspectives on pillar[n]arene-based host–guest
recognition in chemosensing and imaging are outlined.