Surface acoustic wave devices for sensor applications

Liu, Bo; Chen, Xiao; Cai, Hua-Lin; Mohammad, Mohammad Ali; Xia, Tian; Tao, Lei; Yang, Yi; Ren, Tian‐Ling

doi:10.1088/1674-4926/37/2/021001

Cited by 161 publications

(78 citation statements)

References 65 publications

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“…The SAW, which was first described by Lord Rayleigh, refers to the propagation of an acoustic wave along the surface of a piezoelectric material [124]. However, SAW devices could not play an important role in practical applications until White and Voltmer proposed a technique to generate a SAW using interdigital transducers (IDTs) [125] fabricated on the surface of a piezoelectric material.…”

Section: Surface Acoustic Wave (Saw)-based Biosensormentioning

confidence: 99%

Lab-on-a-Chip Systems for Aptamer-Based Biosensing

Khan

Song

2020

Micromachines

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Aptamers are oligonucleotides or peptides that are selected from a pool of random sequences that exhibit high affinity toward a specific biomolecular species of interest. Therefore, they are ideal for use as recognition elements and ligands for binding to the target. In recent years, aptamers have gained a great deal of attention in the field of biosensing as the next-generation target receptors that could potentially replace the functions of antibodies. Consequently, it is increasingly becoming popular to integrate aptamers into a variety of sensing platforms to enhance specificity and selectivity in analyte detection. Simultaneously, as the fields of lab-on-a-chip (LOC) technology, point-of-care (POC) diagnostics, and personal medicine become topics of great interest, integration of such aptamer-based sensors with LOC devices are showing promising results as evidenced by the recent growth of literature in this area. The focus of this review article is to highlight the recent progress in aptamer-based biosensor development with emphasis on the integration between aptamers and the various forms of LOC devices including microfluidic chips and paper-based microfluidics. As aptamers are extremely versatile in terms of their utilization in different detection principles, a broad range of techniques are covered including electrochemical, optical, colorimetric, and gravimetric sensing as well as surface acoustics waves and transistor-based detection.

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Section: Surface Acoustic Wave (Saw)-based Biosensormentioning

confidence: 99%

Lab-on-a-Chip Systems for Aptamer-Based Biosensing

Khan

Song

2020

Micromachines

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“…These provide the advantage of small size due to slower wave velocity at radio frequency (RF) ranges relative to electromagnetic waves, and high efficiency due to reduction of resistive losses compared with similar purely electronic devices. They are compatible with existing integrated circuit (IC) fabrication techniques and can be integrated with other circuit elements [3]. However, as first stated by Helmholtz in 1859 and proved by Rayleigh in 1878, the propagation of acoustic waves in conventional linear media is reciprocal [4]; which is 'requiring the transmission of information or energy between any two points in space to be symmetric for opposite propagating directions' [5].…”

Section: Introductionmentioning

confidence: 99%

Nonreciprocal wave propagation and parametric amplification of bulk elastic waves in nonlinear anisotropic materials

et al. 2020

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Parametric amplification of an elastic wave and a framework for using elastic waves that could enable a new generation of high performance, low noise acoustic amplifiers, mixers and circulators are presented. Using a novel approach with nonlinear materials produces highly desirable non-reciprocal characteristics. Parametric amplification of a weak elastic signal wave is achieved by an elastic pump wave of higher intensity. By careful selection of material orientation together with precise excitation of signal and pump waves, 'up frequency conversion' is suppressed and selective amplification of the elastic signal wave occurs at its original frequency. In addition, a general mathematical framework is developed and used for analytical studies of coupled wave equations in nonlinear anisotropic materials. The results obtained from the analytical studies are verified using a finite element implementation.

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“…To solve this problem, we focused on a solution agitation technology using surface acoustic waves (SAWs) as an actuator . A SAW is a wave in which the energy is concentrated and propagated on the surface of an elastic body.…”

Section: Introductionmentioning

confidence: 99%

“…To solve this problem, we focused on a solution agitation technology using surface acoustic waves (SAWs) as an actuator. [9][10][11] 12,13 In our previous study, we proposed a highly sensitive electrochemical system by combining solution agitation using SAW and the electrochemical detection system μTAS.…”

mentioning

confidence: 99%

Electrochemical characteristics of a hyperthermophilic enzyme in microdroplets stirred and heated by surface acoustic waves

Sakamoto

Shoji

Amaya

et al. 2019

Biotechnology Progress

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Micro total analysis system (μTAS) is expected to be applied in various fields. In particular, since electrochemical measurement is inexpensive and easy, electrochemical measurement can be integrated with a microchannel. However, electrochemical detection sensitivity in a microchannel is lowered because the diffusion of the detection target is limited. In an ordinary electrochemical detection system, using a stirrer in a beaker can overcome limited diffusion. We previously proposed a new detection system that combines a microliquid solution agitation technology using surface acoustic waves (SAWs) with the μTAS. The SAWs function as microstirrers, thus making electrochemical detection possible by overcoming limited diffusion of the sample. However, when the solution is stirred by the SAWs, the temperature of the solution increases to 70°C due to vibrational energy. This leads to enzyme inactivation and impaired electrochemical response. Therefore, in this study, we used a hyperthermophile‐derived enzyme. Temperature and electrochemical characteristics of the detection system using SAWs and a multi‐copper oxidase (MCO) derived from the hyperthermophilic archaea Pyrobaculum aerophilum were studied. Laccase, which is an MCO derived from the thermophilic fungus Trametes versicolor, was also studied. We also characterized the enzyme‐electrochemical reaction using SAWs by comparing the magnitude of the reduction current obtained using the two enzymes with different heat resistances. We observed an increase in the electrochemical response with the SAWs, without impaired enzyme activity. Thus, the use of a thermostable enzyme is suitable for the development of a biosensor that uses SAWs for agitation.

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Surface acoustic wave devices for sensor applications

Cited by 161 publications

References 65 publications

Lab-on-a-Chip Systems for Aptamer-Based Biosensing

Lab-on-a-Chip Systems for Aptamer-Based Biosensing

Nonreciprocal wave propagation and parametric amplification of bulk elastic waves in nonlinear anisotropic materials

Electrochemical characteristics of a hyperthermophilic enzyme in microdroplets stirred and heated by surface acoustic waves

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