Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing Cnidium officinale Extracts

Lee, Myung-Jin; Shim, Youn-Soo; An, So-Youn; Kang, Min-Kyung

doi:10.3390/molecules26051440

Cited by 5 publications

(15 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plaque and bacterial adhesion affect the discoloration of restorations, denture stomatitis, and general health [ 3 , 18 ]. Inhibiting the microbiome prevents denture stomatitis; however, the denture base does not have antifungal properties [ 1 ]. Ideally, dentures should exhibit stable color and surface properties without irritation of the oral mucosa [ 4 , 9 ].…”

Section: Resultsmentioning

confidence: 99%

“…When surface hardness is low, the surface can be easily deformed. It has been shown that the denture surface is affected when cleaning dentures; mechanical cleaning techniques and denture cleansing agents adversely affect the surface by increasing wear and decreasing the stability of dental prostheses [ 1 ].…”

Section: Resultsmentioning

confidence: 99%

“…Toxicity due to denture base materials may cause irritation, inflammation, and allergic reactions in oral tissues [ 1 ]. It is also reported that toxicity can arise from the local effects of toxic substances released from the denture base [ 38 ].…”

Section: Resultsmentioning

confidence: 99%

“…Improvements in medical technology and living standards as well as a greater focus on health have led to a steady increase in human lifespan [ 1 ]. Consequently, the global population is aging [ 2 ], driven by improvements in quality of life.…”

Section: Introductionmentioning

confidence: 99%

“…Many older adults use dentures [ 1 , 4 ]. Acrylic resin, a material for making dentures, has been used in dentistry for a long time and is a dental material that has been improved in terms of its physical properties and biocompatibility [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis

Jung

Lee

2022

Nanomaterials

Self Cite

View full text Add to dashboard Cite

This study investigated the surface properties, biocompatibility, and antifungal activity against Candida albicans of a denture-relining material coated with zinc-bound phosphate-based glass. First, zinc-bound phosphate-based glass was fabricated. A polymerized denture-relining disk was coated with zinc-bound phosphate-based glass (2%, 4%, and 6%). The surface properties of the control and experimental groups were measured, including the wettability, microhardness, color difference, and gloss. The biocompatibility was evaluated using the MTT assay according to ISO 10993-5. The antifungal activity was investigated by counting the number of colony-forming units of Candida albicans. The results were analyzed using a one-way ANOVA and Tukey’s test (p = 0.05). The results of this study indicate that, despite the antimicrobial effect of zinc-bound phosphate-based glass, a coated denture-relining material does not degrade the surface properties and biocompatibility. Therefore, this novel material is considered promising for use as a dental material with antimicrobial properties that can potentially prevent denture stomatitis.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis

Jung

Lee

2022

Nanomaterials

Self Cite

View full text Add to dashboard Cite

show abstract

A review of frequently used Kampo prescriptions. Part 3. Yokukansan

Yamaguchi,

Yoshino,

Oizumi

et al. 2023

Traditional & Kampo Medicine

View full text Add to dashboard Cite

BackgroundThe source of yokukansan (YKS) is thought to be Baoying‐Jinjiang (Hoeikinkyōroku in Japanese) by Xue Ji. YKS was originally designed for children and indicated for spasms, clenching of teeth, digestive dysfunction due to mental instability, and insomnia.Key FindingsYKS formula consists of seven types of crude drugs. Clinical studies have revealed that YKS exerts physiological effects including the treatment of behavioral and psychiatric symptoms of dementia (BPSD), preoperative sedation and anxiety, and postoperative delirium. A meta‐analysis showed that YKS could improve BPSD and daily living activities; however, no improvement in cognitive function was observed. Preclinical studies have also reported that YKS modulates neuronal pathways in the central nervous system, including the serotonergic, glutamatergic, GABAergic, and other neurotransmitter pathways. The incidence of adverse events associated with YKS was 5.17%, with the major adverse effect being pseudoaldosteronism. Routine blood sampling is considered for hypokalemia prevention.ConclusionYKS is useful for BPSD and perioperative mental instability. The modulation of the serotonergic and glutamatergic neural pathways is one of mechanisms. Pseudoaldosteronism is one of the side effects.

show abstract

Establishment of an Efficient In Vitro Propagation of Cnidium officinale Makino and Selection of Superior Clones through Flow Cytometric Assessment of DNA Content

Kim

Han

Lee

et al. 2022

Genes

View full text Add to dashboard Cite

Cnidium officinale is a valuable medicinal plant cultivated in Asia for its rhizomes. This study reports the in vitro regeneration of Cnidium officinale plants and the induction of rhizomes from microshoots. The rhizomatous buds of Cnidium officinale induced multiple shoots on Murashige and Skoog (MS) medium supplemented with 0.5 mg L−1 BA, which led to the regeneration of plants within four weeks of culture. After four weeks of culture, the plants were assessed for fresh weight, the number of leaves, the number of roots, and the length of roots to compare the performance of the different clones. The clones with good growth characteristics were selected with the aid of a flow cytometric analysis of 2C nuclear DNA content. The plants bearing high DNA values showed better growth characteristics. Various factors, namely, sucrose concentration (30, 50, 70, and 90 g L−1), ABA (0, 0.5, 1.0, and 2.0 mg L−1), the synergistic effects of BA (1.0 mg L−1) + NAA (0.5 mg L−1) and BA (1.0 mg L−1) + NAA (0.5 mg L−1) + ABA (1.0 mg L−1) with or without activated charcoal (1 g L−1), and light and dark incubation were tested on rhizome formation from microshoots. The results of the above experiments suggest that MS medium supplemented with 50 g L−1 sucrose, 1.0 mg L−1 ABA, and 1 g L−1 AC is good for the induction of rhizomes from the shoots of Cnidium officinale. Plantlets with rhizomes were successfully transferred to pots, and they showed 100% survival.

show abstract

Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing Cnidium officinale Extracts

Cited by 5 publications

References 25 publications

Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis

Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis

A review of frequently used Kampo prescriptions. Part 3. Yokukansan

Establishment of an Efficient In Vitro Propagation of Cnidium officinale Makino and Selection of Superior Clones through Flow Cytometric Assessment of DNA Content

Contact Info

Product

Resources

About