Surface-Enhanced Resonance Raman Scattering Spectral Probe Based on Functional Nucleic Acid and Nanoparticle

Abstract

Highly sensitive and selective surface-enhanced resonance Raman scattering (SERRS) spectral detection technique are developed by combining the functional nucleic acid (FNA) including aptamer and DNAzyme, and nanoparticle such as gold/silver (NG/NS) aggregation. The recent progress of SERRS was reviewed in this paper.