In this work, physical, chemical and morphological modifications of three different polyamide 6.6 (PA6.6) fabrics were investigated using double barrier dielectric (DBD) plasma treatment. Several techniques of characterization were used to study the effects caused by the interaction between plasma discharge and polyamide fabrics, such as: contact angle, water drop adsorption, Energy Dispersive Spectroscopy (EDS), X-ray Photoelectron Spectroscopy (XPS), Scanning Electron Microscopy (SEM), whiteness by Berger degree and tensile strength. All analyses performed in this study showed that DBD plasma discharge, when applied on PA6.6 fiber, produces significant modifications on the surface of this substrate, without altering its intrinsic properties, thus proving the effectiveness of this important technology to the textile industry.