Surface Modification of Polymer Substrates for Biomedical Applications

Surfaces for hearts: Establishing the optimum plasma surface engineering methodology on polystyrene for cardiac cell engineering

“…In order to maintain all the desired properties for the material and solve the previously mentioned problems in cell affinity and final compatibility, the route of surface modification is typically followed. In recent studies, chemical (for example grafting, oxidation, sulfonation, crosslinking, etching) and physical (for example electron or ion beam, laser treatment, sputtering) techniques are utilised for the surface modification of polymers [7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Comparing to all the aforementioned approaches, plasma surface modification shows a unique dual capability of homogeneous and simultaneous modification of both surface chemistry and topography [21,22].…”

“…surface chemistry and topography [6,[32][33][34][35][36][37][38][39][40]. Recent initial studies, have started to investigate the effect of plasma surface modification on PS for controlling cultured cell functions [11,41].…”