Surface patterned graft copolymerization of hydrophilic monomers onto hydrophobic polymer film upon UV irradiation

Abstract

A random copolymer [p(MMA/DMAB)] composed of methyl methacrylate (MMA) and 2,2-dimethoxy-1,2-di(4-methacryloyloxy)phenylethane-1-one (DMAB), which can simultaneously act as a photoradical initiator and crosslinkable monomer, was prepared by free radical random copolymerization. A hydrophobic film on quartz glass was prepared using p(MMA/DMAB) by a spin-coating technique. Hydrophilic methacrylic acid (MA) and 2-methacryloyloxyethyl phosphorylcholine (MPC) were graft-copolymerized from the hydrophobic p(MMA/DMAB) film in water by photo-cleavage of the DMAB unit. The graft copolymer of MA and MPC was characterized by infrared and X-ray photoelectron spectroscopies and contact angle measurements. To confirm that MPC can be grafted onto the surface of the film selectively at only UV-irradiated sites, photoinduced graft copolymerization of MPC using a photomask was performed to prepare a pMPC patterned p(MMA/ DMAB) film. The film was stained using a rhodamine 6G dye that can absorb specifically to pMPC to confirm the pMPC pattern. The p(MMA/DMAB) film can be applied to various fields including photolithography and biomedical applications, because the film surface properties can be controlled using various vinyl monomers selectively on UV-irradiated sites.

Design and synthesis study of the thermo‐sensitive copolymer carrier of penicillin G acylase

“…Recently, researchers have developed their study to design and copolymerize thermo‐sensitive with other functional monomers to prepare a special material for special use. The study about copolymerization could be separated to random copolymerization, graft copolymerization, block copolymerization, and their combinations . Because block copolymers covalently bonded more than 2 homopolymer segments in its backbone, it can combine the excellent properties of different homopolymers to obtain multifunction polymer materials, and such study has been attracted many researchers.…”

“…The study about copolymerization could be separated to random copolymerization, 31,32 graft copolymerization, 33,34 block copolymerization, 35,36 and their combinations. 37,38 Because block copolymers covalently bonded more than 2 homopolymer segments in its backbone, it can combine the excellent properties of different homopolymers to obtain multifunction polymer materials, and such study has been attracted many researchers. As intelligent materials, the studies about block copolymer that contains thermo-sensitive segment have been extensively reported naturally.…”

Antifouling Stripes Prepared from Clickable Zwitterionic Copolymers

“…Some initial protein and cell manipulation studies have utilized PMPC-patterned surfaces on inorganic substrates using silane coupling chemistry. − An additional report by Enomoto et al offered more flexibility with respect to applications by coating a surface using random copolymers of methyl methacrylate (MMA) and 2,2-dimethoxy-1,2-di­(4-methacryloyloxy)­phenylethane-1-one (DMAB) without relying on surface grafting. By using a photomask to obtain selective UV-irradiated sites, PMPC patterns on MMA/DMAB films were generated via photoinduced polymerization.…”

Thermoresponsive PNIPAM/silica nanoparticles by direct photopolymerization in aqueous media

“…The first step is the synthesis of thiol‐functionalized silica particles (which can be done by one or two substeps), and the second step is the photopolymerization of NIPAM at the surface of thiol‐functionalized silica particles in aqueous media at room temperature, as shown in Scheme . Comparing with existing methods, our method is very simple and facile: immobilization of a photoinitiator and/or use of an additional initiator are not needed; the photopolymerization can be conducted in aqueous media, which has not been extensively studied; and this method could be applied to both thiol‐functionalized SiO 2 nanoparticles and microparticles.…”