Surface Plasmon Resonance Multisensing

Berger, Charles E.H.; Beumer, Tom; Kooyman, R.P.H.; Greve, Jan

doi:10.1021/ac970929a

Cited by 184 publications

(104 citation statements)

References 14 publications

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“…[23,24] Numerous SPR sensors and biosensors were developed, [25][26][27] and metal NPs were implemented to enhance the SPR response and to amplify SPR-based sensors. [28,29] The electronic coupling between the localized plasmon of the metallic NPs (e.g., Au NPs) and the surface plasmon wave enhances the SPR response and, thus, the labeling of recognition complexes with metallic NPs amplifies the sensing events.…”

mentioning

confidence: 99%

Imprinted Au‐Nanoparticle Composites for the Ultrasensitive Surface Plasmon Resonance Detection of Hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX)

2010

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The analysis of explosives attracts recent research efforts due to homeland security needs and the broad demand for the clearance of minefields. While numerous studies have addressed the development of sensing platforms for nitroaromatic explosives, and specifically trinitrotoluene (TNT), the detection of more hazardous explosives, such as hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) or pentaerythritol tetranitrate (PETN), is less developed and needs further efforts, particularly the improvement of the sensitivities associated with the analyses of these substrates.[1,2] Different optical, electrochemical, or microgravimetric sensors or biosensors for TNT were reported. Fluorescent organic polymers, which are quenched by nitroaromatic explosives, [3,4] luminescent polysilole nanoparticles (NPs), [5,6] or fluorescent silicon NPs quenched by nitroaromatic vapors enabled the development of optical sensors. The electrochemical activity of the nitro groups of TNT provided the basis for developing voltammetric sensors for this explosive, [7,8] and recently, a composite of Au NPs linked to electrodes enabled a sensitive electrochemical detection of TNT.[9] Also, different sensing matrices, such as cyclodextrin polymers, [10] carbowax, [11] or silicon polymers, [12] were used for TNT analysis by surface acoustic wave devices, and the aggregation of functionalized Au NPs in the presence of TNT was used to develop an optical sensor for the explosive.[13] Similarly, antibody-based optical [14][15][16] or microgravimetric quartz-crystal-microbalance [17] biosensors for TNT were developed. Different optical [18,19] or voltammetric [20] sensors for RDX were also reported. These included the fluorescence detection of RDX with an acridinium dye, [18] or the application of NADH-functionalized quantum dots.[21] Also, a competitive fluorescence immunoassay for the detection of RDX was reported.[22] The sensitivities accomplished by these methods are, however, unsatisfactory for analyzing trace amounts of the RDX explosive.Surface plasmon resonance (SPR) is a versatile method for probing changes in the refractive index occurring on thin metal films as a result of recognition events or chemical reactions. [23,24] Numerous SPR sensors and biosensors were developed, [25][26][27] and metal NPs were implemented to enhance the SPR response and to amplify SPR-based sensors. [28,29] The electronic coupling between the localized plasmon of the metallic NPs (e.g., Au NPs) and the surface plasmon wave enhances the SPR response and, thus, the labeling of recognition complexes with metallic NPs amplifies the sensing events. Different biosensing processes, such as DNA hybridization, [30] formation of immunocomplexes, [31] and the probing of biocatalytic transformations, [32] used Au NPs as labels for amplified SPR analyses. Recently, composites of bisaniline-crosslinked Au NPs were electropolymerized on Au electrodes, and the resulting matrices were used for the ultrasensitive SPR detection of TNT.[33] The formation of p-donor-acceptor complexes ...

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mentioning

confidence: 99%

Imprinted Au‐Nanoparticle Composites for the Ultrasensitive Surface Plasmon Resonance Detection of Hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX)

2010

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“…This requires both the incidence angle and wavelength of excitation light to be fixed and optimized for best possible sensitivity. In order to improve the measurement throughput, multichannel SPR [4,5] and SPR imaging (SPRi) [6,7] are developed. Figure 1 shows a typical scheme of a prism-based intensity interrogation SPRi setup.…”

Section: Intensity Interrogation Sprmentioning

confidence: 99%

“…So far, the intensity interrogation mode is a straightforward case for 2D arrays. It has been widely used and commercialized by Biacore GE and GWC Technologies for high-throughput analysis in immunosensing [4], DNA hybridization [7], protein interactions [9][10][11], and cellular analysis [12,13]. However, for the detection of multiple interactions simultaneously, it is usually not practical to obtain a homogeneous and optimal response over the entire analyzed surface with the choice of a unique operating point [14].…”

Section: Intensity Interrogation Sprmentioning

confidence: 99%

Recent advances in surface plasmon resonance imaging: detection speed, sensitivity, and portability

et al. 2017

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Surface plasmon resonance (SPR) biosensor is a powerful tool for studying the kinetics of biomolecular interactions because they offer unique real-time and label-free measurement capabilities with high detection sensitivity. In the past two decades, SPR technology has been successfully commercialized and its performance has continuously been improved with lots of engineering efforts. In this review, we describe the recent advances in SPR technologies. The developments of SPR technologies focusing on detection speed, sensitivity, and portability are discussed in details. The incorporation of imaging techniques into SPR sensing is emphasized. In addition, our SPR imaging biosensors based on the scanning of wavelength by a solid-state tunable wavelength filter are highlighted. Finally, significant advances of the vast developments in nanotechnology-associated SPR sensing for sensitivity enhancements are also reviewed. It is hoped that this review will provide some insights for researchers who are interested in SPR sensing, and help them develop SPR sensors with better sensitivity and higher throughput.

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“…Multichannel biosensors are required for direct detection in high-throughput screening systems in the search for new pharmaceuticals. An example of multichannel performance is the biosensor proposed by Berger et al [150] using BIAcore system that demonstrates the feasibility of a multisensing device for monitoring four separate immunoreactions simultaneously in real time. A planar array immunosensor equipped with a charge-coupled device (CCD) as a detector and a diode laser as light source, has been also developed and applied to either the determination of multiple compounds, such as virus, toxins, and bacterial spores in a single sample analysis or a single analyte in multiple samples simultaneously [151][152][153].…”

Section: Multianalyte Determinationmentioning

confidence: 99%

Biosensors for environmental applications: Future development trends

Rodríguez-Mozaz

Marco

Alda

et al. 2004

Pure and Applied Chemistry

199

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Biosensors can be excellent analytical tools for monitoring programs working to implement legislation. In this article, biosensors for environmental analysis and monitoring are extensively reviewed. Examples of biosensors for the most important families of environmental pollutants, including some commercial devices, are presented. Finally, future trends in biosensor development are discussed. In this context, bioelectronics, nanotechnology, miniaturization, and especially biotechnology seem to be growing areas that will have a marked influence on the development of new biosensing strategies in the next future.

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Surface Plasmon Resonance Multisensing

Cited by 184 publications

References 14 publications

Imprinted Au‐Nanoparticle Composites for the Ultrasensitive Surface Plasmon Resonance Detection of Hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX)

Imprinted Au‐Nanoparticle Composites for the Ultrasensitive Surface Plasmon Resonance Detection of Hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX)

Recent advances in surface plasmon resonance imaging: detection speed, sensitivity, and portability

Biosensors for environmental applications: Future development trends

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