Surface, rheopexy, digestive stability and toxicity of olive oil emulsions stabilized by chitin nanocrystals for vitamin D3 delivery

Tradeoff between Amino Group and Crystallinity of Chitin Nanocrystals as a Functional Component in Fluorescent Nail Coatings

“…The typical characteristic peaks are observed in the 13 C solid-state NMR spectra of four prepared ChNCs (Figure 4A), with the chemical shifts located in the range of 103.5−54.8 ppm being attributed to the C1−C6 in glucoside units together with the signals of 173.2 and 22.4 ppm ascribed to N−CH 3 and C�O in acetyl groups. 32 All of the calculated DD values based on the 13 C solid-state NMR results (Table S1) indicated the slight deacetylation of ChNCs during the acid hydrolysis, with DD values of lower than 10%. No matter what the source, the HCl-hydrolyzed ChNCs exhibit higher DD values in comparison to those from H 2 SO 4 -hydrolyzed ChNCs, which may be associated with the longer duration of the conditions in the former than that in the latter.…”

“…The DD values of the prepared ChNCs and dChNC-x were further analyzed by solidstate NMR (CP-MAS NMR) spectroscopy with 13 C cross-polarization, magic-angle spinning, and dipolar decoupling using a Bruker AVANCE 400 NMR spectrometer (Bruker, Germany) operating at 100.61 MHz at room temperature. The contact time was 1 ms with a spinning rate of 10 kHz and pulse intervals of 4 s. The DD values of nanocrystals from NMR results were calculated by the equation 27…”

“…These advantages promote the wide applications of this biomass nanoparticle in composites, food and cosmetic additives, biomedical and energy materials, and functional components for various systems . For instance, ChNC can be used as the reinforcing nanofillers in composites and packaging on the basis of its high modulus and lightweight characteristics. , Due to its biological features, ChNC is potentially applied in biomedical applications in both the bulk and nanoscaled additive, including drug delivery and wound healing and tissue engineering biomaterials as well as an antibacterial component. , Moreover, ChNC has also been reported to be a rheological modifier and stabilizer in foods and emulsions. − All these applications of ChNC are closely associated with its intrinsic physicochemical features or various modifications to tailor the surface properties.…”

The role of nanochitin in biologically-active matrices for tissue engineering-where do we stand?

“…141 They have also designed systems based on self-assembly of positively charged partially deacetylated a-CHNF and negatively charged TEMPO-oxidized cellulose nanofibers, for anticancer drug (5-fluorouracil) delivery 142 and with surrounding pH-depending drug release capacity. 143 Between the systems that incorporate CHNC, we can find both stable emulsions even in the upper digestive system that transport vitamin D3 to the intestine, 144 as well as pH-sensitive hydrogels that are carriers of antibiotics for vaginal administration. 145 Also, partially deacetylated CHNCs demonstrated success as filler of drug delivery systems based on poly(vinyl alcohol), 146 alginate 147 and polyacrylamide/ Zn 2+ hydrogels.…”

Anti-Alzheimer Drug Delivery via Pickering Emulsions Stabilized by Plate-like Cellulose Nanocrystals

“…The electrostatic repulsion of these nanoparticles prevents the formation of a dense stabilizing layer on the oil/water interface. To neutralize this effect, several approaches are used, including the chemical modification of the cellulose nanocrystal surface , and the addition of electrolytes , or oppositely charged particles. , In our previous work, we showed that rod-like CNCs with partially acetylated surfaces have a higher emulsifying ability than sulfated CNC, allowing a reduction of the concentration of electrolyte and the avoided usage of other additives. Therefore, the utilization of acetylated CNC has more prospects in emulsion design.…”