Surface wetting effects in the lipid osmotic pump

Haslam, John L.; Merfeld, Ann E.; Rork, Gerald S.

doi:10.1016/0378-5173(89)90019-7

Cited by 7 publications

(1 citation statement)

References 4 publications

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“…Materials that can produce 5-95% pores and pore sizes in the range of 10-100 μm are beneficial. Different studies have been conducted to study the mechanism of drug release with moderate to high solubility, and some modulators of solubility are also being studied [87]. The thickness of the soluble portion and drug solubility, osmotic pressure, and coating surface area are the factors that affect the drug release rate from this system.…”

Section: Controlled-porosity Osmotic Pumpmentioning

confidence: 99%

Osmotic Pump Drug Delivery Systems—A Comprehensive Review

Almoshari

2022

Pharmaceuticals

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In the last couple of years, novel drug delivery systems (NDDS) have attracted much attention in the food and pharmaceutical industries. NDDS is a broad term that encompasses many dosage forms, one of which is osmotic pumps. Osmotic pumps are considered to be the most reliable source of controlled drug delivery, both in humans and in animals. These pumps are osmotically controlled and release active agents through osmotic pressure. To a large extent, drug release from such a system is independent of gastric fluids. Based on such unique properties and advantages, osmotic pumps have made their mark on the pharmaceutical industry. This review summarizes the available osmotic devices for implantation and osmotic tablets for oral administration.

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Section: Controlled-porosity Osmotic Pumpmentioning

confidence: 99%