Surgery alone versus surgery and doxorubicin for the treatment of feline injection-site sarcomas: a report on 69 cases

Martano, Marina; Morello, Emanuela; Ughetto, Maura; Iussich, Selina; Petterino, Claudio; Cascio, Paolo; Buracco, Paolo

doi:10.1016/j.tvjl.2004.04.004

Cited by 65 publications

(96 citation statements)

References 23 publications

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“…Local excision ('lumpectomy') of FISS is not recommended. In addition to surgery, radiation therapy and/or chemotherapy may be recommended based on consultation with an oncologist [71][72][73][74][75] FISS = feline injection-site sarcoma, SC = subcutaneous, IM = intramuscular Table 6 Indications for the use of inactivated vaccines in cats also other factors that may influence the choice of live versus inactivated vaccines (see Table 6 and Appendix 1 [General FAQs],…”

Section: Remove Tumor Surgicallymentioning

confidence: 99%

2013 AAFP Feline Vaccination Advisory Panel Report

Scherk¹,

Ford

Gaskell

et al. 2013

Journal of Feline Medicine and Surgery

128

111

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Section: Remove Tumor Surgicallymentioning

confidence: 99%

2013 AAFP Feline Vaccination Advisory Panel Report

Scherk¹,

Ford

Gaskell

et al. 2013

Journal of Feline Medicine and Surgery

128

111

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“…One of the widespread prognostic factors for FISS is complete excision with clean margins of neoplasm at the first surgical procedure, which seems to contribute towards an increase in DFI (Davidson et al, 1997;Hershey et al, 2000) and OS (Davidson et al, 1997), although two recent studies reported an absence of correlation between the status of surgical margins and prognosis (Cohen et al, 2001, Martano et al, 2005. The obtainment of clean surgical margins is considered important for predicting local recurrence of FISS (Kobayachi et al, 2002;Giudice et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Poirier et al (2002) observed and increase in DFI, but not in OS, in patients that were submitted to surgery and chemotherapy with doxorubicin or liposomes encapsulated doxorubicin. Martano et al (2005) suggests that chemotherapy with doxorubicin only increases surgical possibilities and extends life expectation for animals with inoperable neoplasms. Barber et al (2000) treated 12 inoperable tumors with a combination of doxorubicin and cyclophosphamide and observed a reduction of up to 50% in tumor size of six patients.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of adjuvant chemotherapy in feline injection site-associated sarcoma

Pereira

Campos

Horta

et al. 2017

Arq. Bras. Med. Vet. Zootec.

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Feline Injection Site-Associated Sarcoma (FISS) is a neoplasm that implies in reduction of quality of life and overall survival in feline patients. A retrospective study of 13 cases of FISS was conducted to evaluate the efficacy of surgical treatment associated to chemotherapy with doxorubicin or carboplatin. Local recurrence occurred in all patients. Patients treated with surgery and chemotherapy presented a longer overall survival and disease-free interval when compared to those that solely received surgical treatment, although no statistical significance was observed (p= 0.3360 and 0.7506, respectively). Surgery remains as the main option for FISS treatment. Further prospective studies with larger samples are warranted to investigate the benefit of chemotherapy for this neoplasm.Keywords: FISS, Doxorubicin, Carboplatin, surgery RESUMO O Sarcoma de Aplicação Felino (SAF) é uma neoplasia associada a redução na qualidade de vida e sobrevida global. O objetivo deste estudo foi avaliar a eficácia da quimioterapia associada à cirurgia no manejo do SAF. Estudo retrospectivo de 13 pacientes com SAF submetidos à cirurgia isolada ou

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“…L'intérêt des radiothérapies (en pré ou postopératoire) semble moins controversé que celui des chimiothérapies [4,6,7,[16][17][18][19]23]. Des traitements à l'interféron sont aussi essayés [22].…”

Section: Le Fibrosarcome Du Chatunclassified

Bénéfices du gui fermenté chez le chat après exérèse de fibrosarcome. Résultats d’une étude préliminaire

Blostin¹,

Faivre

2008

Phytothérapie

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L'objectif de cette étude préliminaire est de vérifier l'efficacité et l'intérêt d'un traitement oral aux extraits de gui fermenté (Viscum album fermenté 1 ) chez des chats, après exérèse de fibrosarcome et comme unique thérapie. Vingtdeux chats ont été suivis lors de cette étude multicentrique. Le traitement est très bien accepté et toléré, n'entraînant aucun effet secondaire. Il semble au moins aussi performant que les traitements classiques actuels les plus efficaces (radiothérapie). La médiane du temps de survie est de 65,4 mois et celle du délai d'apparition d'une récidive, de 53 mois. Ces résultats demandent à être confirmés par d'autres études. Mots clés : Fibrosarcome -Viscum album -ChatValue of a fermented mistletoe extract in the treatment of cats following surgical excision of fibrosarcoma. A preliminary study Abstract: The purpose of this preliminary study was to evaluate the effectiveness and value of oral treatment with a fermented mistletoe extract (fermented Viscum album 1 ) as single therapy in cats, following surgical excision of fibrosarcoma. In this multicentric study of 22 cats, the treatment was very well accepted and tolerated. No side effects were observed. The treatment seems at least as effective as the best current conventional treatment (radiotherapy). Median survival time was 65.4 months and median disease-free interval 53 months. These results need to be confirmed by further studies.

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Surgery alone versus surgery and doxorubicin for the treatment of feline injection-site sarcomas: a report on 69 cases

Cited by 65 publications

References 23 publications

2013 AAFP Feline Vaccination Advisory Panel Report

2013 AAFP Feline Vaccination Advisory Panel Report

Evaluation of adjuvant chemotherapy in feline injection site-associated sarcoma

Bénéfices du gui fermenté chez le chat après exérèse de fibrosarcome. Résultats d’une étude préliminaire

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