Surgery for acute infective endocarditis: epidemiological data from a Spanish nationwide hospital-based registry†

Abstract

Surgical treatment in IE has trended upwards in Spain during the last 2 decades. Patients are getting older and more frequently experience organ dysfunction. Mortality ratio steadily declined without changes in the length of hospital stay.

Infective Endocarditis in Aortic Valve Disease

“…In a study carried out in Spain, Olmos et al observed an increase in incidence, rising from 2.72 cases to 3.49 cases per 100,000 inhabitants/year during the period analysed (2003-2014) [10]. Likewise, Bustamante Munguira et al reported increased IE incidence in Spain, which rose from 3.17% in 1997 to 5.56% in 2014 [9]. In Denmark, Erichsen et al also observed a rise in incidence during 1994-2011, going from 3.93 to 7.55 cases per 100,000 inhabitants a year [11].…”

“…Bustamante Munguira et al, analysing the Spanish series during the time period 1997-2014, found that the percentage of patients requiring surgery increased over the course of the study, reaching 15.7% of the patients [9]. These figures are much lower than those of the European registry, in which the Euro Heart Survey reported a rate of 58.7% [29].…”

“…Data on the incidence of the disease have been updated in the last few years by the publication of various studies of an epidemiological nature. The most recent ones report an incidence of 3-10 cases per 100,000 inhabitants/year, but there is great geographical variability in the data [1][2][3][4][5]9]. Over the last few years, several groups have published incidences from local studies that give us a geographical view of the current IE situation.…”

“…This method makes it possible to analyse broad population samples over long period of time, but the fact that it lacks clinical content is a decided weakness. This is the case with the Spanish series, in which the minimum basic data set of the National Surveillance System for Hospital Data in Spain provided by the Spanish Ministry of Health was used [9]. In Italy, Cresti et al used the Health Care System Hospital Discharge Records database with a primary or secondary International Classification of Diseases 9th Revision IE diagnosis code [12].…”

Surgical Aspects of Infective Endocarditis with Focus on the Aortic Root

“…After antibiotics were introduced in clinical practice in 1928 by Sir Alexander Fleming, the mortality of the disease dramatically dropped (3) . However, despite new and improved antibiotics, mortality remains high, between 10 and 25% according to published series (4)(5)(6)(7)(8)(9)(10)(11) .…”