2022
DOI: 10.1371/journal.pone.0271173
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Surgery versus IVF for the treatment of infertility associated to ovarian and deep endometriosis (SVIDOE: Surgery Versus IVF for Deep and Ovarian Endometriosis). Clinical protocol for a multicenter randomized controlled trial

Abstract: The management of endometriosis-related infertility is still a challenging issue. Women can be managed with either surgery or in vitro fertilization (IVF). The decision is tailored to the patients considering pros and cons of both approaches. Surgery might increase the chances of natural conception and relieve symptoms. IVF may be more effective, but costs are higher and unoperated women face some peculiar additional risks during the procedure and pregnancy. The unavailability of randomized trials comparing th… Show more

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Cited by 7 publications
(3 citation statements)
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“…Instead, individualized treatment plans, considering patient’s specific circumstances and preferences, should be the goal. Currently ongoing multicentric trials may provide deeper understanding of the comparative effectiveness of the different treatment options, including surgery and ARTs ( 27 ).…”
Section: Discussionmentioning
confidence: 99%
“…Instead, individualized treatment plans, considering patient’s specific circumstances and preferences, should be the goal. Currently ongoing multicentric trials may provide deeper understanding of the comparative effectiveness of the different treatment options, including surgery and ARTs ( 27 ).…”
Section: Discussionmentioning
confidence: 99%
“…Endometriosis affects 10% to 15% of women of reproductive age, and up to 25% to 50% of women with infertility have endometriosis . Currently, in women affected, infertility can be managed with either surgery or assisted reproduction technology (ART) . In women with endometriosis who undergo autologous in vitro fertilization (IVF) procedures, success rates have been reported to be lower compared with women without the disease .…”
Section: Introductionmentioning
confidence: 99%
“… 1 , 2 , 3 , 4 Currently, in women affected, infertility can be managed with either surgery or assisted reproduction technology (ART). 5 In women with endometriosis who undergo autologous in vitro fertilization (IVF) procedures, success rates have been reported to be lower compared with women without the disease. 3 An increased risk of unexpected poor response to ovarian stimulation and a lower number of retrieved oocytes beyond the well-known detrimental effects of surgery for ovarian endometriomas have been associated with the disease.…”
Section: Introductionmentioning
confidence: 99%