Surgical adhesives

Abstract

The authors have performed a literature review of surgical adhesives, such as cyanoacrylate, collagen gelatin, and fibrin glue. They have included different types of commercial and non-commercial fibrin sealants and have reported on the different components in these adhesives, such as fibrinogen, cryoprecipitate, bovine thrombin, and thrombin-like fraction of snake venom

The new heterologous fibrin sealant in combination with low-level laser therapy (LLLT) in the repair of the buccal branch of the facial nerve

“…At the time of use, the components were previously thawed, reconstituted, mixed, and applied according to the following protocol: The first bottle had fibrinogen obtained from buffalo blood (5 μl), the second contained calcium chloride (2 μl), and the last bottle had a thrombin-like fraction (1 μl), totaling 8 μl [16,[23][24][25][26].…”

Mesenchymal stem cells engrafted in a fibrin scaffold stimulate Schwann cell reactivity and axonal regeneration following sciatic nerve tubulization

“…At the time of use, the components were thawed, reconstituted, mixed and applied (Thomazini-Santos et al, 2001;Barros et al, 2009Barros et al, , 2011Gasparotto et al, 2014;Barbizan et al, 2013). The fibrin glue was composed of three separate solutions, as mentioned above, and homogenized immediately before use in a final volume of 6 l: (1) fibrinogen (3 l), (2) calcium chloride (2 l) and (3) thrombin-like fraction (1 l).…”

A new heterologous fibrin sealant as scaffold to recombinant human bone morphogenetic protein-2 (rhBMP-2) and natural latex proteins for the repair of tibial bone defects

“…At the time of use, the components were previously thawed, reconstituted, mixed and applied according to the protocol of the project (Thomazini-Santos et al, 2001;Barros et al, 2009Barros et al, , 2011Gasparotto et al, 2014;Ferreira, 2014).…”