Surgical Gamma Probe with TlBr Semiconductor for Identification of Sentinel Lymph Node

Costa, F.E.; Rela, P.R.; Oliveira, Iria Bárbara de; Pereira, M.C.C.; Hamada, M.M.

doi:10.1109/nssmic.2005.1596935

Cited by 9 publications

(13 citation statements)

References 7 publications

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“…There are criteria that guide the evaluation of radioguided probes in this type of application and define the minimum necessary requirements. 31 has shown that the physical characteristics have met the suggested proposals in international publications to be used as radioguided probes in the location of sentinel lymph nodes, marked with 99m Tc. Oliveira-Filho et al…”

Section: Discussionmentioning

confidence: 78%

“…Costa et al 31 reported that because of the high penetrability of gamma rays,radiation can be detected in any part of the patient and not only at the desired area. This situation implies that the detection should not only present high energy resolution, but also the capability to spatially reject undesirable gamma rays which might be reflected over the detector.…”

Section: Discussionmentioning

confidence: 99%

“…Today, there are several pieces of equipment commercially available to carry out the intraoperatory gamma detection such as Neoprobe ® , Europrobe ® , Navigator ® . However, most pieces of equipment are imported and expensive, which a lot of times limits their use to large centers 31,32 . They basically have a probe with a crystal or small gamma camera in one end, which is connected to a portable counter.…”

Section: Introductionmentioning

confidence: 99%

“…Costa et al 31 have developed a piece of national intraoperatory gamma detection equipment, which has a radioguided surgical probe. They carried out tests with doctors that found the device friendly to use and aimed to get the product to the market at a lower cost.…”

Section: Introductionmentioning

confidence: 99%

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National equipment of intraoperatory gamma detection in the identification of sentinel lymph node in animal model

Santos

Nahas

et al. 2009

Acta Cir. Bras.

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Purpose: To investigate a national equipment of intraoperatory gamma detection in the identification of sentinel lymph node. Methods: Thirty young adult male rats were used. After anesthetized, animals were divided into two groups of 15 animals each. Animals from group A received dextram 500 -Tc 99 radiopharmaceutical and patent blue V and those from group B received only patent blue V to map the lymphatic drainage. The presence of radiation in the background area, in the area of injection and of the ex vivo sentinel lymph node of group A were measured. After the exeresis, each lymph node in group A and in group B was mixed forming a new random sequence and the radioactive reading of each lymph node was carried out, using both pieces of equipment. Results: The hottest sentinel lymph node was identified by the national equipment when radiation was measured in the area of limphatic drainage after the Dextran 500 was injected. Also, the ex vivo sentinel lymph node. The national equipment has also detected radiation in the lymph nodes that had not received radiopharmaceutical, leading to false positive, checked by the application of Mann-Whitney tests and Student's paired t-tests. The Cronbach alpha has shown high internal consistency of data 0,9416. Conclusions: The national equipment of intraoperatory gamma detection identifies the LS and showed false positives LS and needs improvement. Key words: Sentinel Lymph Node Biopsy. Equipment. Research Design. Rats. RESUMO Objetivo:Investigar o equipamento nacional de detecção gama intra-operatória na identificação de linfonodo sentinela. Métodos: Foram utilizados 30 ratos machos, adultos jovens. Depois de anestesiados, os animais foram distribuidos em dois grupos de 15 animais cada. O grupo A recebeu radiofármaco dextran 500 -Tc 99 e azul patente V e o grupo B, somente azul patente V para realização do mapeamento linfático. Foi realizada a medição da captação radioativa da região de fundo, do sítio de injeção e do linfonodo sentinela ex vivo do grupo A. Após a exérese, cada linfonodo do grupo A e do grupo B foram misturados formando uma nova seqüência aleatória e procedeu a leitura da radioatividade de cada linfonodo com os dois equipamentos. Resultados: O linfonodo sentinela hipercaptante foi identificado pelo equipamento nacional durante as medições da captação radioativa na região do sítio de injeção e linfonodo sentinela ex vivo. O equipamento nacional detectou radiação mesmo nos linfonodos que não receberam o radiofármaco, causando falso positivo, verificado na aplicação dos testes de Mann-Whitney e t pareado de Student. O alfa de Cronbach mostrou alta consistência interna dos dados (0,9416). Conclusões: O equipamento nacional de detecção gama intra-operatória identifica o linfonodo sentinela e mostra falsos positivos e necessita de aprimoramento. Descritores: Biópsia de Linfonodo Sentinela. Equipamento. Projetos de Pesquisa. Ratos.

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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National equipment of intraoperatory gamma detection in the identification of sentinel lymph node in animal model

Santos

Nahas

et al. 2009

Acta Cir. Bras.

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“…In our previous works [2], [5], [11], the detectors were made with two electrodes and all of them showed the polarization effect with the aleatory pulse formation after a shorter period of bias application in the detectors, compared to that with 3 electrodes, as used in this work. Also, the progressive charge collection reduction, occurred with the two-electrode detector, was not observed with the three-electrode detector.…”

Section: Resultsmentioning

confidence: 98%

Temperature dependence in the long-term stability of the TlBr detector

Costa

Hamada

2008

2008 IEEE Nuclear Science Symposium Conference Record

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In this paper, the temperature dependence in the long term stabDity of the TlBr detector was studied. Systematic measurements of the pulse height spectra and counting rate were carried out. The pulse height spectra showed poor hole collection, worsening with the increase of temperature. The ratemeter measurements showed an aleatory pulse formation that may be attributed to the polarization effect and air moisture in the detector environment.

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