Surgical Results of Large and Giant Pituitary Adenomas with Special Consideration of Ophthalmologic Outcomes

Müslüman, Ahmet Murat; Cansever, Tufan; Yılmaz, Adem; Kanat, Ayhan; Oba, Ersin; Çavuşoğlu, Halit; Sirinoglu, Deniz; Aydın, Yunus

doi:10.1016/j.wneu.2011.02.009

Cited by 73 publications

(43 citation statements)

References 40 publications

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“…Patients, who maintain their treatment and attendance to appointments for periodic reviews, have good outcome, with a improve of their visual impairments and hormonal levels, treated by hormonal substitution. It has been observed that patients with pre-operative anterior dysfunction recover function after surgery and the cases who presented with visual disturbance improve their vision with a second surgery (Chang et al, 2010;Müslüman et al, 2011). …”

Section: Discussionmentioning

confidence: 99%

Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study

Ortíz-Plata¹,

Tena-Suck²,

Pérez-Neri³

et al. 2012

Pituitary Adenomas

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Section: Discussionmentioning

confidence: 99%

Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study

Ortíz-Plata¹,

Tena-Suck²,

Pérez-Neri³

et al. 2012

Pituitary Adenomas

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“…Since then, investigators have attempted to identify pre-operative characteristics that may predict recovery. Variables such as age, duration of symptoms, tumour size and volume, pre-operative visual acuity (VA) or visual field (VF) loss, optic atrophy and pattern electroretinogram have been explored but none has been able to consistently predict visual recovery following surgery [3][4][5][6][7][8][9][10][11][12][13][14][15]. Such predictors of visual outcome would be helpful to allow counseling of patients in relation to their ultimate likely visual function as well as tailoring of management strategies regarding the timing of surgery.…”

Section: Introductionmentioning

confidence: 99%

Optical coherence tomography predicts visual outcome for pituitary tumors

Danesh‐Meyer¹,

Wong²,

Papchenko³

et al. 2015

Journal of Clinical Neuroscience

133

102

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“…Rekurensi dari adenoma hipofisis setelah pengangkatan komplit dilaporkan terjadi pada 10-25 % pasien, biasanya terjadi pada 4 tahun pertama. [16][17][18] b. Terapi Radiasi Terapi radiasi merupakan sebuah pilihan yang dianjurkan, untuk beberapa alasan. Pada studi yang lebih dulu, tera-pi radiasi direkomendasikan sebagai pengobatan primer untuk semua jenis tumor hipofisis, khususnya pada pasienpasien yang memiliki faktor risiko buruk untuk operasi.…”

Section: Diagnosaunclassified

“…Insidens invasi dural pada tumor hipofisis dilaporkan pada 40% pasienpasien Mayo Clinic. 16,17 Tumor hipofisis biasanya dianggap jinak dan merupakan lesi terbatas, tumbuhnya lambat, sehingga insidensi dengan fenomena keganasan mengejutkan banyak pihak. Oleh karena itu, tumor hipofisis berlaku seperti meningioma, yang dapat menginvasi dura dan tulang lebih mudah daripada otak.…”

Section: Diagnosaunclassified

Adenoma Hipofisis

Hidayat¹

2015

MKA

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AbstrakAdenoma hipofisis diklasifikasikan berdasarkan beberapa kriteria yaitu klinis dan endokrin, patologi, serta radiologi. Klasifikasi endokrin membedakan tumor sebagai fungsional dan nonfungsional, berdasarkan aktivitas sekretorinya in-vivo. Klasifikasi patologi berusaha untuk membatasi kelompok tumor heterogenus secara klinis dan patologis dengan kategori yaitu asidofilik, basofilik, dan kromofobik. Klasifikasi radiologi mengelompokkan tumor hipofisis berdasarkan ukuran dan karakteristik pertumbuhan, yang dapat ditemukan dari studi imaging. WHO membuat klasifikasi yang mencoba untuk mengintegrasikan semua klasifikasi yang ada dan menyediakan sinopsis praktis untuk aspek klinis dan patologis dari adenoma. Diagnosa adenoma hipofisis dibuat berdasarkan: gejala klinis dari gangguan hormon, adanya riwayat penyakit dahulu yang jelas, pemeriksaan fisik yang menunjang, pemeriksaan laboratorium yang menunjukkan disfungsi dari hormon yang terganggu, adanya pemeriksaan penunjang yang akurat seperti CTScan, MRI-Scan. Jenis, besar dan fungsi dari tumor sangat menentukan dalam mempertimbangkan penatalaksanaan dari adenoma hipofisis. Pengobatan diindikasikan pada semua pasien dengan gejala, terutama dengan hipogonadisme. Pilihan terapi termasuk kontrol dengan obat-obatan, reseksi bedah, dan terapi radiasi. AbstractPituitary adenomas are classified according to several criteria; clinical endocrine, pathology, and radiology. Endocrine classification distinguishes tumors as functional and nonfunctional, based on in-vivo secretory activity. Pathology classification seeks to restrict clinically heterogeneous group of tumors and pathological categories namely acidophilic, basophilic, and kromofobik. Radiological classification classifies pituitary tumors by size and growth characteristics, which can be found on imaging studies. WHO made a classification that attempts to integrate all existing classifications and provide practical synopsis for the clinical and pathological aspects of adenoma. Diagnosis of pituitary adenoma is made based on: clinical symptoms of hormonal disorders, clear past medical history, clear physical examination, laboratory tests show hormonal dysfunction or disturbance, and accurate investigations such as CT scan and MRI scan. Types, large and function of the tumor is crucial in considering the management of pituitary adenomas. Treatment is indicated in all patients with symptoms, especially with hypogonadism. Therapeutic options include control with drugs, surgical resection and radiation therapy.

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Surgical Results of Large and Giant Pituitary Adenomas with Special Consideration of Ophthalmologic Outcomes

Cited by 73 publications

References 40 publications

Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study

Pituitary Adenomas – Clinico-Pathological, Immunohistochemical and Ultrastructural Study

Optical coherence tomography predicts visual outcome for pituitary tumors

Adenoma Hipofisis

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