1954
DOI: 10.1016/s0039-6109(16)34235-9
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Surgical Risk of the Elderly Asthmatic

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1955
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“…Cortisone and ACTH have also been advocated for the supportive treatment of patients who have poor adrenocortical function, and who may not have the wherewithal to tolerate the stress of operation (144–149). Fromer (150) and Adams and Souders (151) reported that in some cases of asthma or emphysema, a course of corticotropin will provide maximal improvement in pulmonary function. The use of these steroids should be tempered, however, by the knowledge that when given over a long period of time they may induce excess retention of fluid and adrenal insufficiency (152).…”
Section: Preoperative Considerationsmentioning
confidence: 99%
“…Cortisone and ACTH have also been advocated for the supportive treatment of patients who have poor adrenocortical function, and who may not have the wherewithal to tolerate the stress of operation (144–149). Fromer (150) and Adams and Souders (151) reported that in some cases of asthma or emphysema, a course of corticotropin will provide maximal improvement in pulmonary function. The use of these steroids should be tempered, however, by the knowledge that when given over a long period of time they may induce excess retention of fluid and adrenal insufficiency (152).…”
Section: Preoperative Considerationsmentioning
confidence: 99%
“…Because the administration of cortisone depresses normal adrenal function, the amount given should be increased on the day of operation to 300 mg., with progressively smaller daily doses thereafter. Fromer (8) has recommended that an infusion of 15 to 30 mg. of ACTH in 500 cc. of 5 per cent glucose in distilled water be given over each six‐ to eight‐hour period during an acute asthmatic episode.…”
Section: Preoperative Preparationmentioning
confidence: 99%