Surgical-site infection in gynecologic surgery: pathophysiology and prevention

Steiner, H; Strand, Eric A.

doi:10.1016/j.ajog.2017.02.014

Cited by 72 publications

(60 citation statements)

References 73 publications

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“…Health care-associated infections (HAI) are acquired by patients while receiving care, and represent the most frequent adverse event affecting patient safety worldwide [1]. It is estimated that hundreds of millions of patients are affected by HAIs each year, leading to significant mortality and financial losses for health systems [2,3]. Currently evidences shows that SSI is the most surveyed and frequent type of HAI in low and middle-income countries and affects nearly one third of patients who have undergone a surgical procedure [4].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of surgical site infection and its associated factors after cesarean section in Ethiopia: systematic review and meta-analysis

Getaneh

Negesse

Dessie

2020

BMC Pregnancy Childbirth

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Background: Surgical site infection (SSI) affects nearly one third of patients who have undergone a surgical procedure. It is a significant and substantial cause of surgical patient morbidity and mortality later with human and financial costs threat. There are fragmented and pocket studies which reported the prevalence of SSI among mothers who experienced for cesarean section and its risk factors. However, there is no any solid evidence established at the national level; which was also the interest of the authors to fill this gap. Therefore, this systematic review and meta-analysis aimed to estimate the pooled prevalence of SSI after cesarean section and its associated factors at national level. Methods: Original articles were searched in PubMed, MEDLINE, EMBASE, CINAHL, Google Scholar, HINARI portal, and Cochrane Library. All observational studies defined outcome of variable "SSI as infection related to an operation procedure that occur at or near surgical incision within 30 days of operation or after one year if an implant is placed" were considered. Data were extracted using standard data extraction excel spread sheet checklists developed according to 2014 Joanna Briggs Institute Reviewers' Manual after the quality was assessed through Newcastle-Ottawa quality assessment scale. The I 2 statistic was used to quantify heterogeneity across studies. Funnel plot asymmetry and Egger's tests were used to check for publication bias. A fixed effect model was used to estimate the pooled prevalence of SSI. Odds Ratio (OR) with 95% Confidence Interval (CI) was also considered to determine the association of identified variables with SSI. Statistical analysis was conducted using STATA version 14 software. Result: From initial 179 identified articles, 11 were eligible for inclusion in the final systematic review and metaanalysis. Studies with a score of 6 and above were included for final analysis. All included studies were institutional based cross sectional. The pooled estimate of SSI after cesarean section in Ethiopia was 9.72% (95%CI: 8.38, 11.05).

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Section: Introductionmentioning

confidence: 99%

Prevalence of surgical site infection and its associated factors after cesarean section in Ethiopia: systematic review and meta-analysis

Getaneh

Negesse

Dessie

2020

BMC Pregnancy Childbirth

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“…Cesarean section was performed for prerupture of membranes (pre‐ROM) in 194 and 104 patients pre‐ and postoptimization, respectively, and for postrupture of membranes (post‐ROM) in 46 and 32, respectively. Regarding the SSI risk factors, age, body mass index (BMI), diabetes mellitus, gestational diabetes mellitus, blood transfusion, drain insertion and the number of cases with a prolonged operative time did not change pre‐ and postoptimization, and pre‐ and post‐ROM adjustment (Table ).…”

Section: Resultsmentioning

confidence: 99%

Prevention of surgical site infection via antibiotic administration according to guidelines after gynecological surgery

Toba

Moriwaki

Oshima

et al. 2018

J of Obstet and Gynaecol

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“…Rationale: Approximately 2% of all hysterectomies are complicated by SSI 71 with perioperative hyperglycemia (defined as blood glucose >180e200 mg/dL) being a known risk factor. 72 Perioperative blood glucose control may decrease the risk of SSI.…”

Section: Level Of Evidence: Lowmentioning

confidence: 99%

Surgical technical evidence review for gynecologic surgery conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery

Kalogera

Nelson²,

Liu

et al. 2018

American Journal of Obstetrics and Gynecology

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Surgical-site infection in gynecologic surgery: pathophysiology and prevention

Cited by 72 publications

References 73 publications

Prevalence of surgical site infection and its associated factors after cesarean section in Ethiopia: systematic review and meta-analysis

Prevalence of surgical site infection and its associated factors after cesarean section in Ethiopia: systematic review and meta-analysis

Prevention of surgical site infection via antibiotic administration according to guidelines after gynecological surgery

Surgical technical evidence review for gynecologic surgery conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery

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