Survival in Persons With Traumatic Spinal Cord Injury Receiving Structured Follow-Up in South India

Barman, Apurba; Shanmugasundaram, Devika; Bhide, Rohit; Viswanathan, Anand; Magimairaj, Henry Prakash; Nagarajan, Guru; Arumugam, Elango; Tharion, George; Thomas, Raji

doi:10.1016/j.apmr.2013.11.003

Cited by 10 publications

(6 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the study by Varma et al ., [ 10 ] gender was not significant by univariate analysis however after adjustment for confounders by multivariable logistic regression modeling, a 60 percent higher chance of death in males compared with females was seen (OR=1.6). In all studies, the association of higher age and mortality was assessed which showed a significant relationship in all except one [ 29 ]; this study compared patients less than 20 years old with older subjects.…”

Section: Resultsmentioning

confidence: 99%

Mortality Rate and Predicting Factors of Traumatic Thoracolumbar Spinal Cord Injury; A Systematic Review and Meta-Analysis

Azarhomayoun¹,

Aghasi²,

Mousavi³

et al. 2018

BEAT

View full text Add to dashboard Cite

Objective:To estimate the summation of mortality rate and the contributing factors in patients with traumatic thoracolumbar spinal cord injuries (TLSCI). Methods:A systematic search of observational studies that evaluated the mortality associated with TLSCI in MEDLINE and EMBASE was conducted. The study quality was evaluated using a modified quality assessment tool previously designed for observational studies.Results:Twenty-four observational studies involving 11,205 patients were included, published between January 1, 1997, and February 6, 2016. Ten studies were of high quality, thirteen were of moderate quality, and one study was of low quality. Seventeen reports described risk factors for mortality and eleven of these studies used a multiple regression models to adjust for confounders. The reported mortality rate ranged from 0 to 37.7% overall and between 0 and 10.4% in-hospital. The sum of mortality for in-hospital, 6-month, and 12-month were 5.2%, 26.12%, 4.3%, respectively. The mortality at 7.7 years follow-up was 10.07% and for 14 years follow-up reports ranged from 13.47% to 21.46%. Associated data such as age at injury, male to female ratio, pre-existing comorbidities, concomitant injuries, duration of follow-up, and cause of death have been underreported in studies investigating the mortality rate after TLSCI.Conclusion:There is no study was found that accurately assessed mortality in the thoracolumbar spine, while there is general agreement that traumatic thoracolumbar spinal cord injuries are important.

show abstract

Section: Resultsmentioning

confidence: 99%

Mortality Rate and Predicting Factors of Traumatic Thoracolumbar Spinal Cord Injury; A Systematic Review and Meta-Analysis

Azarhomayoun¹,

Aghasi²,

Mousavi³

et al. 2018

BEAT

View full text Add to dashboard Cite

show abstract

“…That study reported survival of 86% 5 years after discharge in a sample of 537 patients discharged from a tertiary rehabilitation facility between 1981 and 2011. 12 The authors reported an impressive 91% follow-up rate. However, the sample only included those in whom the hospital kept medical records on following discharge.…”

Section: Introductionmentioning

confidence: 87%

“…This decision was made with the knowledge that~390 eligible patients are admitted to the CRP each year 14,15 and with the expectation that a 2-year survival would be between 65% and 85%. [9][10][11][12][13] With a sample size of 390 and a survival of 75%, the estimated precision of an estimate of survival is better than ± 5%.…”

Section: Setting and Participantsmentioning

confidence: 99%

“…1,[5][6][7][8] The few studies that have looked at survival after discharge in LMICs (Zimbabwe, Nepal, Sierra Leone and Bangladesh) report survival ranging from 30 to 75% between 1 and 5 years after discharge. [9][10][11][12][13] These studies are either very small or have high losses to follow-up so they do not provide precise and rigorous estimates of survival.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Two-year survival following discharge from hospital after spinal cord injury in Bangladesh

et al. 2015

View full text Add to dashboard Cite

Study design: Mixed retrospective-prospective cohort study. Objectives: To determine 2-year survival following discharge from hospital after spinal cord injury in Bangladesh. Setting: Bangladesh. Methods: Medical records were used to identify all patients admitted in 2011 with a recent spinal cord injury to the Centre for Rehabilitation of the Paralysed, a large Bangladeshi hospital that specialises in care of people with spinal cord injury. Patients or their families were subsequently visited or contacted by telephone in 2014. Vital status and, where relevant, date and cause of death were determined by verbal autopsy. Results: 350 of 371 people admitted with a recent spinal cord injury in 2011 were discharged alive from hospital. All but eleven were accounted for two years after discharge (97% follow-up). Two-year survival was 87% (95% CI 83% to 90%). Two-year survival of those who were wheelchair-dependent was 81% (95% CI 76% to 86%). The most common cause of death was sepsis due to pressure ulcers. Conclusion: In Bangladesh, approximately one in five people with spinal cord injury who are wheelchair-dependent die within two years of discharge from hospital. Most deaths are due to sepsis from potentially preventable pressure ulcers.

show abstract

“…30 Similarly, rehabilitation facilities are inadequate in number and protocols for management of SCI. 31 Distance to care and limited care facilities likely contribute, as rural location significantly increased in-hospital severe neurological deficits.…”

Section: Discussionmentioning

confidence: 99%

Social Determinants of Health Impact Spinal Cord Injury Outcomes in Low- and Middle-Income Countries: A Meta-Epidemiological Study

Covell,

Naik,

Shaffer

et al. 2023

Neurosurgery

View full text Add to dashboard Cite

BACKGROUND AND OBJECTIVES: Traumatic spinal cord injuries (SCI), which disproportionally occur in low- and middle-income countries (LMICs), pose a significant global health challenge. Despite the prevalence and severity of SCI in these settings, access to appropriate surgical care and barriers to treatment remain poorly understood on a global scale, with data from LMICs being particularly scarce and underreported. This study sought to examine the impact of social determinants of health (SDoH) on the pooled in-hospital and follow-up mortality, and neurological outcomes, after SCI in LMICs. METHODS: A systematic review was conducted in adherence to the Preferred Reporting in Systematic Review and Meta-Analysis-guidelines. Multivariable analysis was performed by multivariable linear regression, investigating the impact of the parameters of interest (patient demographics, country SDoH characteristics) on major patient outcomes (in-hospital/follow-up mortality, neurological dysfunction). RESULTS: Forty-five (N = 45) studies were included for analysis, representing 13 individual countries and 18 134 total patients. The aggregate pooled in-hospital mortality rate was 6.46% and 17.29% at follow-up. The in-hospital severe neurological dysfunction rate was 97.64% and 57.36% at follow-up. Patients with rural injury had a nearly 4 times greater rate of severe in-hospital neurological deficits than patients in urban areas. The Gini index, reflective of income inequality, was associated with a 23.8% increase in in-hospital mortality, a 20.1% decrease in neurological dysfunction at follow-up, and a 12.9% increase in mortality at follow-up. CONCLUSION: This study demonstrates the prevalence of injury and impact of SDoH on major patient outcomes after SCI in LMICs. Future initiatives may use these findings to design global solutions for more equitable care of patients with SCI.

show abstract

Survival in Persons With Traumatic Spinal Cord Injury Receiving Structured Follow-Up in South India

Cited by 10 publications

References 28 publications

Mortality Rate and Predicting Factors of Traumatic Thoracolumbar Spinal Cord Injury; A Systematic Review and Meta-Analysis

Mortality Rate and Predicting Factors of Traumatic Thoracolumbar Spinal Cord Injury; A Systematic Review and Meta-Analysis

Two-year survival following discharge from hospital after spinal cord injury in Bangladesh

Social Determinants of Health Impact Spinal Cord Injury Outcomes in Low- and Middle-Income Countries: A Meta-Epidemiological Study

Contact Info

Product

Resources

About