Sustained-Release Bupropion for Pharmacologic Relapse Prevention after Smoking Cessation

Hays, J. Taylor; Hurt, R. Douglas; Rigotti, Nancy A.; Niaura, Raymond; Gonzales, David; Durcan, Michael J.; Sachs, David P.L.; Wolter, Troy D.; Buist, A. Sonia; Johnston, J. Andrew; White, J. D.

doi:10.7326/0003-4819-135-6-200109180-00011

Cited by 334 publications

(230 citation statements)

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“…⅐ Clinical trials should include primary outcomes related to quality of life and oncology treatment. ⅐ Quality of life assessment may include global measures [86][87][88][89] and site-specific measures. 90 Other tobacco use ⅐ Assess change in use of spit tobacco (e.g., chewing tobacco, snuff), pipes; cigars, or other forms of tobacco after a cancer diagnosis.…”

Section: Area Of Research Recommendationmentioning

confidence: 99%

Nicotine dependence treatment for patients with cancer

Cox

Africano

Tercyak

et al. 2003

Cancer

135

118

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A semifluidized bed was proposed to allay bed plugging during the filtration of fines‐hydrocarbon suspensions. Mitigation of plugging was allowed by alternating semifluidization during capture with unconstrained fluidization for removal of deposits. Solids holdup conditions were established to prevent deposition in the fluidization section. The cyclic parameters were varied to allow efficient removal of deposits during washing. Analysis with a filtration model accounting for solids detachment in the fixed bed section revealed that the fluidization section favored growth of aggregate size entering the fixed bed. Analysis of the split ratios between fixed and fluidized bed heights revealed that the shallowest fluidization sections delayed deposition in the fixed bed. In cyclic operation, reversibility of the semifluidized bed was best recovered via gas injection during the washing stages. However, the filtration times in successive cycles shortened with increasing washing times but lengthened with increasing the washing superficial suspension velocity. © 2008 American Institute of Chemical Engineers AIChE J, 2008

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Section: Area Of Research Recommendationmentioning

confidence: 99%

Nicotine dependence treatment for patients with cancer

Cox

Africano

Tercyak

et al. 2003

Cancer

135

118

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“…Repeated intervention and extended treatment are expected to improve abstinence rates (Shiffman et al, 2004;Durcan et al, 2002;Gonzales et al, 2001;Hays et al, 2001;Hall et al, 2004). Data show that many smokers who relapse following biobehavioral intervention will successfully achieve abstinence with subsequent pharmacotherapy for smoking cessation (Shiffman et al, 2004;Durcan et al, 2002;Gonzales et al, 2001).…”

Section: Discussionmentioning

confidence: 99%

Design and baseline characteristics from the KAN-QUIT disease management intervention for rural smokers in primary care

Cox

Cupertino

Mussulman

et al. 2008

Preventive Medicine

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Objective-To describe the design, implementation, baseline data, and feasibility of establishing a disease management program for smoking cessation in rural primary care.Method-The study is a randomized clinical trial evaluating a disease management program for smoking cessation. The intervention combined pharmacotherapy, telephone counseling, and physician feedback, and repeated intervention over two years. The program began in 2004 and was implemented in 50 primary care clinics across the State of Kansas.Results-Of eligible patients, 73% were interested in study participation. 750 enrolled participants were predominantly Caucasian, female, employed, and averaged 47.2 years of age (SD=13.1). In addition to smoking, 427 (57%) had at least one additional major risk factor for cardiovascular disease (diabetes, hypertension, high cholesterol, heart disease or stroke). Participants smoked on average 23.7 (SD=10.4) cigarettes per day, were contemplating (61%) or preparing to quit (30%), were highly motivated and confident of their ability to quit smoking, and reported seeing their physicians multiple times in the past twelve months (Median=3.50; Mean=5.48; SD=6.58).Conclusion-Initial findings demonstrate the willingness of patients to enroll in a two-year disease management program to address nicotine dependence, even among patients not ready to make a quit attempt. These findings support the feasibility of identifying and enrolling rural smokers within the primary care setting.

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“…Son Cochrane metaanalizde de bupropion kullanan olgularda sigara bırakma başarısının plasebodan anlamlı oranda daha yüksek olduğu bildirilmiştir (OR: 1.85; Güvenlik aralığı: %95; 1.63-2.1) (16) . Sigara bırakmada bupropion kullanımı bir yıllık bırakmış kalma oranı ve sigara yoksunluk semptomlarını önlemede plaseboya göre daha başarılı ve güvenlidir (17) .…”

Section: Bupropion Tedavisinin Klinik Etkinliğiunclassified