Sutureless coronary artery bypass with biologic glued anastomoses: Preliminary in vivo and in vitro results

Gundry, Steven R.; Black, Kirby S.; Izutani, Hironori

doi:10.1067/mtc.2000.108596

Cited by 89 publications

(48 citation statements)

References 5 publications

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“…8) Moreover, BioGlue TM demonstrated very effective sealing properties, even strong enough for sutureless coronary anastomosis in an experimental animal model. 9) Nevertheless, there are also reports of possible drawbacks of BioGlue TM . LeMaire, et al showed that BioGlue TM causes aortic growth impairment and anastomotic strictures in pediatric patients, 10) whereas Erasmi and coworkers reported a major inflammatory response after repair of a dissecting descending aortic aneurysm.…”

Section: Discussionmentioning

confidence: 99%

Control of Suture Hole Bleeding After Aortic Valve Replacement by Application of BioGlueTM During Circulatory Arrest

2005

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SUMMARYBleeding from suture holes in aortic valve replacement (AVR) may represent a difficult problem especially if the aortic wall is friable. We describe a case in which suture hole bleeding after AVR was present at the posterior aortic wall close to the pulmonary artery. Following several attempts to suture the leak using felt pledget armed prolene sutures, deep hypothermic circulatory arrest was induced and BioGlue TM in combination with Tabotamp TM was applied for successful sealing of the bleeding source. (Int Heart J 2005; 46: 175-179)

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Section: Discussionmentioning

confidence: 99%

Control of Suture Hole Bleeding After Aortic Valve Replacement by Application of BioGlueTM During Circulatory Arrest

2005

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“…An advantage of the MVP® over other automated devices 16,17 is that even if the insertion attempt fails, the device may be removed and the vessel wall will be found to have remained intact and the intimal surface undamaged.…”

Section: Discussionmentioning

confidence: 99%

“…Other distal anastomotic devices have also been used for coronary artery bypass grafting, but not in minimally invasive surgery. [15][16][17][18][19] The short time required to perform these anastomoses is a major advantage in off-pump coronary artery bypass grafting and MIDCAB procedures because regional coronary artery flow is interrupted a relatively short time (146 seconds in this series) while inserting the device. Even in standard operations, morbidity is reduced because of the shortened duration of cardiopulmonary bypass.…”

Section: Discussionmentioning

confidence: 99%

Magnetic Vascular Port in Minimally Invasive Direct Coronary Artery Bypass Grafting

et al. 2004

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Background-Minimally invasive direct coronary artery bypass grafting (MIDCAB) is a well-established operative procedure. However, it is technically demanding and is therefore somewhat underused. We evaluated the clinical and angiographic outcome of patients undergoing a MIDCAB procedure with the Ventrica Magnetic Vascular Port (MVP®) system. Methods and Results-A Ventrica MVP® system was used in 10 of 11 selected MIDCAB patients. The system consists of 6 magnetic clips, with 3 clips forming a set. One magnetic clip set is positioned at the arteriotomy of the target artery and of the bypass graft using a preloaded delivery system. These ports then form an anastomosis by magnetic coupling. The mean age of the 10 patients (6 male) was 60.3Ϯ11.0 years. Three patients had an angiogram at the time of discharge and 8 returned for a 6-month angiogram. The total procedure time was 128.2Ϯ12.2 minutes. The mean anastomotic time was 199 seconds. The mean ischemic time during the anastomosis was 146Ϯ146 seconds. There were no in-hospital complications and no device-related adverse events. All 3 predischarge and all 8 6-month angiograms showed patent anastomoses. Conclusions-The magnetic vascular port facilitates the MIDCAB procedure significantly and reduces the ischemic time during the anastomosis. This minimally invasive procedure has the potential to be an alternative to percutaneous transluminal coronary angioplasty and stenting in proximal left anterior descending (LAD) stenosis. It may expand the acceptance of hybrid procedures in which a left internal mammary artery (LIMA)-to-LAD graft optimally supplies the anterior wall and the septum while the circumflex and right coronary artery may be treated interventionally.

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“…Over the last years, there have been major industrial developments to create a mechanical anastomosis between a saphenous vein graft and the coronary artery [1][2][3][4][5][6] or between a saphenous vein graft and the aorta [7][8][9]. A nitinol connector that facilitates a non-penetrating, sutureless vein graft to coronary artery anastomosis, developed by Converge Medical, Inc., Sunnyvale, CA, is intended to create an end-to-side 308 elliptical coronary anastomosis.…”

Section: Introductionmentioning

confidence: 99%

First clinical results with a 30° end-to-side coronary anastomosis coupler☆

Boening

Schoeneich

Lichtenberg

et al. 2005

European Journal of Cardio-Thoracic Surgery

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Sutureless coronary artery bypass with biologic glued anastomoses: Preliminary in vivo and in vitro results

Abstract: A biologic glue and catheter system has been developed that allows a coronary anastomosis with a high bursting strength to be performed. When the system has been further developed and tested, truly minimally invasive heart surgery may be possible.

Cited by 89 publications

References 5 publications

Control of Suture Hole Bleeding After Aortic Valve Replacement by Application of BioGlueTM During Circulatory Arrest

Control of Suture Hole Bleeding After Aortic Valve Replacement by Application of BioGlueTM During Circulatory Arrest

Magnetic Vascular Port in Minimally Invasive Direct Coronary Artery Bypass Grafting

First clinical results with a 30° end-to-side coronary anastomosis coupler☆

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