Switch-type near-infrared fluorescent probes for Hg2+ based on rhodamines

Wu, Linyun; Wang, Xing; Huang, Jie; Wei, Haiyan; Kan, Chun

doi:10.1016/j.jphotochem.2022.113936

Cited by 25 publications

(11 citation statements)

References 37 publications

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“…In 2022, Wu et al designed and synthesized a fluorescent sensor RBLY with a fast response to Hg 2+ and high selectivity by introducing sulfur atoms. 224 Compared to traditional rhodamine fluorescent probes, RBLY is a near-infrared molecular probe, which is more conducive to fluorescence imaging in biological environments (Fig. 25).…”

Section: Rhodamine Derivatives For Bioimagingmentioning

confidence: 99%

Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

et al. 2023

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Section: Rhodamine Derivatives For Bioimagingmentioning

confidence: 99%

Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

et al. 2023

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“…[9][10][11][12][13] Among these strategies, systems based on Hg 2+ -promoted deprotection reactions have attracted much attention due to their ion-specific selectivity and high sensitivity. [14][15][16][17][18][19][20][21][22][23][24] Based on the intramolecular charge transfer mechanism, the mercaptan-protected aldehyde group (thioacetal) can be converted into the original aldehyde group in the presence of Hg 2+ . [25][26][27][28][29][30] Several thioacetal derivatives of fluorophores have been developed in fluorescent probes for Hg 2+ detection.…”

Section: Introductionmentioning

confidence: 99%

Pyrene‐Based “Turn‐On” Fluorescent Polymeric Probe with Thioacetal Units in the Main Chain for Mercury(II) Detection in Aqueous Solutions and Living Cells

Gu,

Li,

et al. 2024

Macromol. Rapid Commun.

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A water‐soluble polymeric pyrene‐based polythioacetal (PTA‐Py) with thioacetal units in the main chain is simply synthesized by direct polycondensation of 3, 6‐dioxa‐1, 8‐octanedithiol, 1‐pyrene formaldehyde, and mPEG2k‐SH. The probe PTA‐Py shows a good fluorescence response to Hg2+ ions due to the Hg2+‐promoted deprotection reaction of thioacetal groups to regenerate the original 1‐pyrene formaldehyde compound. After adding Hg2+ to the PTA‐Py solution, the fluorescence intensity (FI) gradually increases with increasing concentrations of Hg2+. Compared with other metal ions, the probe exhibits high sensitivity, good selectivity, and rapid response to Hg2+. The low detection limits are 12.3 nm in ethanol‐PBS buffer and 13.3 nm in water, respectively. The results imply that the simply synthesized water‐soluble polymeric probe had potential applications in the rapid detection of Hg2+ ions in aqueous solutions. Moreover, the polymeric PTA‐Py shows high sensitivity for CH3Hg+ with detection limits of 26.5 nm in ethanol/PBS buffer. In addition, PTA‐Py can efficiently detect Hg2+ ions in HeLa cells. The results demonstrate that a valuable method is developed for biocompatible polymeric sensors for Hg2+ ions in biological and environmental samples.

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“…In recent years, many fluorescent probes have been reported for detecting N 2 H 4 in living cells [13][14][15][16][17][18][19][20][21][22]. Near-infrared fluorescent probes (650-900 nm) are particularly suitable for detecting small molecules in vivo, because they cause little damage to tissue and have good tissue penetration [24,[26][27][28][29][30][31][32][33][34][35][36].…”

Section: Introductionmentioning

confidence: 99%

“…Near‐infrared fluorescent probes (650–900 nm) are particularly suitable for detecting small molecules in vivo , because they cause little damage to tissue and have good tissue penetration [24, 26–36]. Dicyanoisophorone analogues have been widely used in near‐infrared fluorescent probe design because of their simple synthesis and large Stokes’ shift [27, 37–40].…”

Section: Introductionmentioning

confidence: 99%

A near‐infrared fluorescent probe for detecting hydrazine metabolized from isoniazid in living cells

Pang,

An,

Miao

et al. 2024

Luminescence

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Isoniazid is a drug for treating tuberculosis, but hydrazine (N2H4), the major metabolite of isoniazid, can cause hepatotoxicity. Therefore, monitoring the content of N2H4 in time is of great significance for studying the hepatotoxicity induced by isoniazid. In this study, a near‐infrared fluorescent probe (BC‐N) was designed and synthesized based on the specific reaction of acetyl ester with N2H4. BC‐N exhibits excellent selectivity, sensitivity, and biocompatibility. In addition, BC‐N is applied in the visualization of N2H4 produced from isoniazid in living cells and is a potential tool for monitoring hepatotoxicity induced by isoniazid.

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Switch-type near-infrared fluorescent probes for Hg2+ based on rhodamines

Cited by 25 publications

References 37 publications

Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

Pyrene‐Based “Turn‐On” Fluorescent Polymeric Probe with Thioacetal Units in the Main Chain for Mercury(II) Detection in Aqueous Solutions and Living Cells

A near‐infrared fluorescent probe for detecting hydrazine metabolized from isoniazid in living cells

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