Symmetrical thalamic calcifications in a monozygotic twin: case report and literature review

Buldini, Barbara; Drigo, Paola; Via, Luigi Dalla; Calderone, Milena; Laverda, Anna Maria

doi:10.1016/j.braindev.2004.04.002

Cited by 9 publications

(3 citation statements)

References 9 publications

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“…Symmetrical echogenicity in the thalami can also be seen in latepreterm or full-term infants who are considered to have had an acute antenatal insult, even though the history is not always clear. 64,65 The abnormalities are usually recognized with cUS and become more marked with time (►Fig. 4).…”

Section: Perinatal Arterial Ischemic Strokementioning

confidence: 99%

Progress in Neonatal Neurology with a Focus on Neuroimaging in the Preterm Infant

2015

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There have been tremendous changes in the methods used to evaluate brain injury in the preterm infant in the past 30 years. In particular, major improvements have been made in how we use neuroimaging techniques and now magnetic resonance imaging (MRI) is used more often and considered complimentary to routine and sequential cranial ultrasound. The focus has shifted from severe lesions such as large intraventricular and parenchymal hemorrhages and cystic periventricular leukomalacia to assessing and understanding the etiology of more subtle noncystic white matter injury, punctate hemorrhage, and cerebellar lesions. The more severe lesions that dominated the early period of preterm neonatal brain imaging occur less frequently but are still associated with major disabilities, such as, cerebral palsy, while subtle white matter injury and cerebellar lesions are more often associated with cognitive and behavioral problems, which have become the most prevalent issues among the survivors of extremely preterm birth.

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Section: Perinatal Arterial Ischemic Strokementioning

confidence: 99%

Progress in Neonatal Neurology with a Focus on Neuroimaging in the Preterm Infant

2015

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“…En outre, des lésions isolées de la substance grise contractées dans la période prénatale ont été confirmées après la naissance [68,69].…”

Section: Tableau De L'enfant Prématuréunclassified

Asphyxie périnatale et infirmité motrice d’origine cérébrale (I- Le diagnostic)

Boog

2010

Gynécologie Obstétrique & Fertilité

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“…1 This condition has also been referred to as symmetrical thalamic calcifications (STC). 2,3 STL is a specific neuropathological entity, often following an acute antenatal insult but the etiology is not always known and still a matter of debate. It differs from a postnatal (mostly unilateral) hemorrhage or bilateral ischemic injury in the thalamus following a severe perinatal hypoxic-ischemic event.…”

Section: Introductionmentioning

confidence: 99%

Symmetrical Thalamic Lesions in the Newborn: A Case Series

et al. 2019

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Although bilateral injury to the thalami is often seen in (near)term infants with hypoxic ischemic encephalopathy (HIE), symmetrical thalamic lesions (STL) is a different, very rare condition, seen both in full-term and preterm infants often after an antenatal insult, although the history is not always clear. These lesions are usually first detected using cranial ultrasound (cUS). They may not always be seen on the first (admission) scan, but become apparent in the course of the 1st week after birth. Clinically, these infants present with hypo- or hypertonia, absence of sucking and swallowing reflexes, and they may have contractures and facial diplegia. Neuropathology commonly demonstrates a thalamic lesion with additional and variable involvement of basal ganglia and brainstem. The prognosis is very poor, the condition often leads to severe disabilities and/or death within the first years of life. The clinical course and neuroimaging findings of 13 patients with symmetrical thalamic lesions (STL) are reported.

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Symmetrical thalamic calcifications in a monozygotic twin: case report and literature review

Cited by 9 publications

References 9 publications

Progress in Neonatal Neurology with a Focus on Neuroimaging in the Preterm Infant

Progress in Neonatal Neurology with a Focus on Neuroimaging in the Preterm Infant

Asphyxie périnatale et infirmité motrice d’origine cérébrale (I- Le diagnostic)

Symmetrical Thalamic Lesions in the Newborn: A Case Series

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